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LABOKLIN (UK)| Genetic Diseases | Cats| Polydactyly (extra toes) / polydactylism / Polydactyl / hyperdactyly
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Maine Coon Special offer:
8 DNA tests for just £84.95 incl VAT
Maine Coon 8 DNA tests bundle (HCM, SMA, PKDef, Poly, b, b1, cb, cs) 

Bengal Special offer:
4 Bengal Specific DNA tests for just £72.00 incl VAT
Bengal DNA bundle (rdAc-PRA + b-PRA + PK-Def + Blood Groups) 

British Special offer:
4 Breed Specific DNA tests for just £72.00 incl VAT
British Short / Long Hair DNA bundle (PKD + pd-PRA + ALS + Blood Groups)

Burmese Special offer:
4 Breed Specific DNA tests for just £72.00 incl VAT
Burmese DNA bundle (Hypokalemia (BHK) + Head Defect + Gangliosidosis (GM2) + Blood Groups

Birman Special offer:
5 Breed Specific DNA tests for just £72.00 incl VAT
Birma DNA bundle (PKD + pd-PRA + Hypotrichiose + MPS6 + Blood Groups)

Maine Coon Special offer:
5 Breed Specific DNA tests for just £72.00 incl VAT
Maine Coon DNA bundle (HCM1 + SMA + PK-Def + F11 + Blood Groups)

Ragdoll Special offer:
5 Breed Specific DNA tests for just £72.00 incl VAT
Ragdoll DNA bundle (HCM1 + HCM3 + PKD + pd-PRA + Blood Groups)

Norwegian Special offer:
4 Breed Specific DNA tests for just £72.00 incl VAT
Norwegian Forest DNA bundle (PK-Def + Amber + GSD4 + Blood Groups)

Feline Special Offer:
8 cat DNA tests for just £84.95 including VAT
HCM, HCR, GSD4, PKD, PRA, PK-Def., SMA, Blood Groups

new test:      Paradoxical Pseudomyotonia (PP) in English Cocker and English Springer Spaniels  
new test:      Dyserythropoietic Anemia and Myopathy Syndrome (DAMS) in English Springer Spaniel
new test:      Lysosomal Storage Diseases (LSD) in Dalmatian and Doberman  
new Kennel Club DNA testing schemes with LABOKLIN:
   Osteochondrodysplasia (OCD) / Skeletal Dwarfism in Miniature Poodles
  DINGS2: Deafness with Vestibular Dysfunction in Doberman
   Dyserythropoietic Anemia and Myopathy Syndrome (DAMS) in English Springer Spaniel

Polydactyly (extra toes) / polydactylism / Polydactyl / hyperdactyly

Test number: 8874
Gene: Polydactyly
Price: £ 48.00 (including VAT)
Abyssinian , All Cat Breeds , American Curl Longhair , American Curl Shorthair , American Shorthair , American Wirehair , Anatoli , Turkish Angora , Arabian Mau , Australian Mist , British Shorthair (BSH) , Balinese , Bengal (Leopard cat) , Birman (Sacred cat of Burma) , Bombay , Brazilian Shorthair , British Longhair (BLH) , Burmese , Burmilla , Canadian Sphynx , Cat / Feline , Ceylon cat , Chartreux , Chausie , Colorpoint Shorthair , Colourpoint , Cornish Rex , Crossbred / Mixed Breed , Cymric cat , Domestic Longhair , Domestic Shorthair , Devon Rex , Donskoy (Don Sphynx / Russian Hairless) , Egyptian Mau , European Shorthair , Exotic Shorthair , Foldex , German Longhair , German Rex , Himalayan , Japanese Bobtail Longhair , Japanese Bobtail Shorthair , Javanese , Kanaani , Korat , Kurilian Bobtail , LaPerm Longhair , LaPerm Shorthair , Maine Coon , Manx cat , Munchkin , Nebelung , Neva Masquerade , Norwegian Forest Cat , Ocicat , Ojos Azules , Oriental Longhair (OLH , Oriental Shorthair (OSH) , Persian , Persian Ragdoll , Persian Related , Peterbald , Pixie Bob Longhair , Pixie Bob Shorthair , Ragdoll , Ragdoll Related , Russian Blue , Savannah , Scottish Fold Longhair , Scottish Fold Shorthair , Selkirk Rex Longhair , Selkirk Rex Shorthair , Serengeti , Seychellois , Siamese , Siberian , Singapura , Snowshoe , Sokoke , Somali , Sphynx , Thai , Tonkinese , Toybob , Toyger , Turkish Van , Ural Rex , Various cat breeds .
Trait of Inheritance
Mutations resulting in polydactyly are known to be inherited as an autosomal dominant trait with high penetrance.

Inheritance : AUTOSOMAL DOMINANT trait

Polydactyly (extra toes) / polydactylism / Polydactyl / hyperdactyly (HW, UK1, UK2)

Polydactyly is a congenital physical anomaly, which causes the cat to be born with more than the usual number of toes on one or more of its paws.

Polydactyly is not painful for cats, and it is not known to be associated with any health problems and doesn't cause any health problems.

Polydactyly (extra toes) is a harmless anatomical anomaly commonly seen in Maine coon cats.

In Maine coon cats, polydactyly is caused by a mutation called the ‘Hemingway mutation’ (Hw) in the ZRS gene. This gene is involved in the formation of digits in paws. The Hw mutation causes different phenotypes and is very variable in expression. Cats with the Hw mutation can have up to 8 extra toes, however this can vary from only an enlargement of the standard dew claw, or making it a thumb (so still 5 toes), or only one poly paw (6 toes). Therefore, polydactyly varies from very minor expression (like only a nub) to having several extra digits.

Mitten Paws: this is when the cat has extra ‘thumb’ toes makes the paws look like mittens.

A total of three mutations have been identified so far in polydactyl cats: the Hw mutation in Maine coon and PixieBob cats, and the UK1 and UK2 mutations in British domestic short hair cats.

There are other , yet, unidentified mutations which cause polydactyly, for example the Canadian lines of polydactyl Maine coon cats don’t have the Hw, UK1 or UK2 mutations.

Furthermore, the mutation which is responsible for ‘pattyfoot’ (extra toes but no ‘thumb’) has not yet been identified and cannot be detected by this test.

Sample Requirements
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.
2-3 weeks
£ 48.00 (including VAT)

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See also:

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