Canine Glaucoma and Goniodysgenesis (GGD) in Border Collie
Goniodysgenesis is a developmental abnormality of the eye's anterior chamber which is strongly associated with glaucoma and blindness. This abnormality affects the drainage pathway and so fluid in the eye isn't drained properly leading to increase in the pressure of fluid inside the eye (Intra Ocular Pressure IOP), which damages the optic nerve and may cause loss of vision.
GGD is caused by a mutation in Olfactomedin-like 3 (OLFML3) which has recently been identified by researchers at the The Roslin Institute and Royal (Dick) School of Veterinary Studie and Mater Research Institute-UQ.
Symptoms include:severe pain in the eye, watery eye, high sensitivity to light, winking spasms, dilated pupils, raised third eyebrow, etc
A DNA test is now available at Laboklin and will help you in finding out if a dog is genetically clear, carrier or affected and plan breeding so that you avoid having affected puppies.