Adverse behaviours such as seizure, “glazing over”, episodic biting, and general loss of clarity, has been reported in the Belgian Malinois and attributed to certain genetic variants in the dopamine transporter gene.
The test detects certain genetic variants in the SLC6A3 gene which are known to be associated with owner reports of seizure, “glazing over” behaviours, episodic biting behaviours, and general loss of clarity in the Belgian Malinois. These polymorphisms have further been associated with increased aversive treatment of dogs by handlers, and increased stress in dogs in response to handlers. The association between these polymorphism(s) and behaviour/seizure has only been confirmed in the Belgian Malinois. Due to the complex nature of behaviour, it is possible that environmental factors such as stress may contribute to the expression of adverse owner-reported behaviours.