Autoimmune lymphoproliferative syndrome (ALPS) is an inherited disease found in British Shorthair cats. Symptoms starts around the age of 6-8 weeks. Affected kittens develop rapidly progressive and marked generalized lymphadenopathy (enlargement of the lymph nodes), moderate splenomegaly (enlargement of the), and regenerative and likely hemolytic anemia.
Symptoms progresses quickly within 2-3 week and affected kittens usually die or eutheniased only few weeks after the start of clinical symptoms.