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Cystinuria (Feline Cystinuria) (CY)
Test number: 8604
Gene: CY Price: £ 48.00 (including VAT)
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The Disease |
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Cystinuria is an inherited metabolic disease that is relatively common in dogs, but rare in cats. The condition is characterized by defective amino acid reabsorption, leading to the formation of cystine stones in the kidney, ureter and the bladder (cystine urolithiasis). This can lead to urinary obstruction.
The kidneys are involved in the filtration of the blood. Kidneys process the blood through filtration, reabsorption, secretions and excretion. In the first step, the blood is filtered. Cells, proteins and other large molecules are retained, while smaller molecules are filtered into an ultrafiltrate that will eventually become urine. Then, water (~55%) and electrolytes are reabsorbed from the ultrafiltrate back into the blood system and terminal metabolic products (waste products) are secreted from the blood into the ultrafiltrate. Finally, ultrafiltrate is excreted into the ureters, where it becomes urine. Through this process of filtration and excretion, kidneys help maintain homeostasis in the kitty’s body. In cystinuria, however, the amino acid cysteine is inadequately reabsorbed from the ultrafiltrate. This results in excessive cysteine concentrations in the urine and can lead to the formation of cystine uroliths.
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Description |
Cystinuria is a genetic metabolic disease characterized by a selective proximal renal tubular defect affecting cystine, ornithine, lysine, and arginine (COLA) reabsorption, which can lead to uroliths (the formation of stony concretions in the bladder or urinary tract) and urinary obstruction. A DNA test is now available for Cystinuria in Cats at Laboklin.
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Price
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£ 48.00 (including VAT)
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See also: |
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HCM 1 (Hypertrophic Cardiomyopathy)
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HCM4 ( Hypertrophic Cardiomyopathy HCM 4) in Sphynx
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HCM (Hypertrophic Cardiomyopathy HCM3/HCR)
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PKD (Feline Polycystic Kidney Disease)
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PK Deficiency (Pyruvate Kinase Deficiency)
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Progressive Retinal Atrophy ( rdAc - PRA )
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SMA (Spinal Muscular Atrophy )
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Serological Evaluation of blood Groups
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Hypokalemia / Familial Episodic Hypokalaemic Polymyopathy (BHK)
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Head Defect (BHD)
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Alpha-Mannosidosis (AMD)
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Congenital Myasthenic Syndrome (CMS) / Hereditary Myopathy
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Gangliosidosis GM1
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Gangliosidosis GM2
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Gangliosidosis GM2
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Mucopolysaccharidosis Type VI (MPS VI MPS6)
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Mucopolysaccharidosis type VII (MPS VII / MPS7)
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Myotonia Congenita (Fainting Goat)
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Progressive Retinal Atrophy (pd-PRA)
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Progressive Retinal Atrophy (rdy-PRA)
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Hypotrichosis and Short Life Expectancy
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Progressive Retinal Atrophy in Bengal (PRA-b / b-PRA)
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Special Offer: HCM, HCR, GSD4, PKD, PRA, PK-Def., SMA, Blood Groups
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Osteochondrodysplasia (Scottish Fold Osteodystrophy)
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Primary Congenital Glaucoma (PCG)
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Persian DNA bundle (PKD + pd-PRA + AMD + Blood Groups)
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British Short / Long Hair DNA bundle (PKD + pd-PRA + ALPS + Blood Groups)
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Burmese DNA bundle (Hypokalemia (BHK) + Head Defect + Gangliosidosis (GM2) + Blood Groups
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Birma DNA bundle (PKD + pd-PRA + Hypotrichiose + MPS6 + Blood Groups)
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Bengal DNA bundle (rdAc-PRA + b-PRA + PK-Def + Blood groups)
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Maine Coon DNA bundle (HCM1 + SMA + PK-Def + FXI + Blood Groups)
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Ragdoll DNA bundle (HCM1 + HCM3 + PKD + pd-PRA + Blood groups)
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Norwegian Forest DNA bundle (PK-Def + Amber + GSD4 + Blood groups)
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Siamese / Oriental DNA bundle (GM1 + MPS6 + PCG + rdAc-PRA + Blood Groups)
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Sphynx DNA bundle (HCM4 + Hypokalemia + CMS + Blood groups)
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Acrodermatitis enteropathica in Felis catus
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Factor XI deficiency ( F11 )
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MDR1 Gene Defect
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Skeletal Dysplasia
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Factor 12 FXII cat
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Devon Rex DNA bundle (CMS + Blood Groups + Long Coat + Rex Hair)
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Siberian DNA Bundle (Blood Groups + PK-Def + Dilution + Colourpoint)
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Genetic Blood groups in cats
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LABOGenetics XXL Cat - Comprehensive Feline DNA bundle
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Autoimmune Lymphoproliferative Syndrome (ALPS)
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Polydactyly (extra toes) / polydactylism / Polydactyl / hyperdactyly
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Unlisted DNA test
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Congenital Hypothyroidism (CH)
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Maine Coon 8 DNA tests bundle (HCM, SMA, PKDef, Poly, b, b1, cb, cs)
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Blue Eyes
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Glycogen Storage Disease ( GSD ) Type IV
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