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LABOKLIN (UK)| Coat Colours / Length | Cats| Dominant White / White Spotting
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Dominant White / White Spotting

Test number: 8591

Breed
All Cat Breeds .
Description

Dominant White (W) and White Spotting (ws) are found across many breeds of cats and result from the insertion of a common 'feline endogenous retrovirus' in the KIT gene. A full 7125bp insertion results in White Spotting while a partial insertion results in Dominant White. Only one copy of the full insertion is required for the White Spotting color pattern when the other allele is wild-type. While the extent of White Spotting is not definitively associated with copy number, anecdotal evidence suggests that two copies of the white spotting insert results in more white. The pattern of white spotting does not correlate with one or two copies and the gene/genes controlling the pattern of White Spotting remain unknown. Additionally, not all white spots or patterns result from these alleles as other genes can also have mutations that result in depigmentation phenotypes., One or two copies of the partial insert results in the Dominant White (W) phenotype regardless of the other allele. Dominant White is distinct from albinism © which results from a mutation in a different gene that has no known impact on hearing. While one or two copies of the W allele will result in a white cat, varying degrees of hearing impairment are observed. In an extended pedigree, nearly 75% of cats with two copies were deaf and the remainder had at least partial hearing impairment.

Results report:

Test Result Dominant White & White Spotting
w/w Normal - no copies of the Dominant White or White spotting mutations
W/w

1 copy of the Dominant White mutation; cat is White

W/W

2 copies of the Dominant White mutation; cat is White

ws/w 1 copy of White spotting, cat has white spotting
W/ws 1 copy each of Dominant White and White spotting mutations; cat is White
ws / ws 2 copies of the white spotting mutation; cat has white spotting

White or almost white cats often have blue eyes, amber eyes or one amber and one blue eye.

Sample Requirements
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.
Turnaround
2 - 3 weeks
Price
Number of Coat Colour Tests on the same cat Price (including VAT)
First Colour test £ 48.00
Each additional colour test on the same cat £ 24.00

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