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**NEW**



Bengal Special offer:
3 Bengal Specific DNA tests for just £60.00 incl VAT
Bengal DNA bundle (rdAc-PRA + b-PRA + PK-Def) 



British Special offer:
3 Breed Specific DNA tests for just £60.00 incl VAT
British Short / Long Hair DNA bundle (PKD + pd-PRA + ALS)



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3 Breed Specific DNA tests for just £66.00 incl VAT
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4 Breed Specific DNA tests for just £66.00 incl VAT
Birma DNA bundle (PKD + pd-PRA + Hypotrichiose + MPS6)



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3 Breed Specific DNA tests for just £60.00 incl VAT
Maine Coon DNA bundle (HCM1 + SMA + PK-Def)



Ragdoll Special offer:
4 Breed Specific DNA tests for just £60.00 incl VAT
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Norwegian Special offer:
3 Breed Specific DNA tests for just £60.00 incl VAT
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Feline Special Offer:
8 cat DNA tests for just £79.95 including VAT
HCM, HCR, GSD4, PKD, PRA, PK-Def., SMA, Blood Groups

new test: Cocoa (Chocolate / Brown ) in French Bulldog
new test: Stargardt disease ( STGD )  and  Copper storage disease - Copper toxicosis (CT) in Labrador Retriever
new test: Inflammatory Pulmonary Disease ( IPD ) in Rough and Smooth Collies
new test: Lafora Disease in Basset Hound, Beagle, Chihuahua, French Bulldog, Welsh Corgi and Mini Wirehaired Dachshund
new Kennel Club DNA testing schemes with LABOKLIN:
• Pug Dog Encephalitis (PDE) / Necrotizing Meningoencephalitis (NME) in Pug
• Progressive Retinal Atrophy (prcd-PRA) and • Progressive retinal atrophy ( rcd4-PRA) / LOPRA in Standard Poodle
• Dwarfism ( Chondrodysplasia / disproportinate short-limbed ) and • Primary Open Angle Glaucoma (POAG) in Norwegian Elkhounds


Panda White Spotting

Test number: 8578

Breed
German Shepherd .
Trait of Inheritance
.

Inheritance : AUTOSOMAL DOMINANT trait
Description

A mutation in the KIT-gene is associated with a white spotting pattern in German Shepherd Dogs, this pattern is also knopwn as Panda White Spotting. The mutation is very recent, it appeared spontaneously in a female born in 2000. The mutation in German Shepherds is in a different gene from the gene that causes white spotting in other breeds. This mutation should not be confused with the S Locus gene that causes white spotting in other breeds. The Panda Spotting mutation causes white markings on the the face, limbs, belly, neck, and the tip of the tail, with the white being concentrated toward the front of the dog. The amount of white can vary from one dog to another.

The trait of inheritance is autosomal dominant which means that one copy of the mutation is sufficient to cause the Panda White Spotting (N/P), however, it is important to note that dogs with two copies of the mutation (P/P) have not been found and are likley to die during gestation and will be reabsorped into the womb.

Carriers (N/P) (one copy of the mutation) have not expressed any health issues associated with the Panda pattern.

The mutation the causes the Panda White Spotting occurs in the KIT-gene. This gene has two alleles P and N. The P is dominant. One copy of the P allele results (N/P) in dogs with the Panda white pattern. Two copies of the P allele result in early embryonic death.

Sample Requirements
Buccal Swabs or 0.5 - 1 ml blood in EDTA Blood Tube
Buccal swabs or 0.5 - 1 ml blood in EDTA Blood Tube .
Price
Number of Coat Colour Tests on the same dog Price (including VAT)
First Colour test £ 48.00
Each additional colour test on the same dog £ 24.00

To order:

  • Download Order Form from this link pdf

  • Complete the order form and send it together with your samples to the following address:

    Laboklin (UK),   125 Northenden Road, Manchester, M33 3HF




new test:
Androgen Insensitivity Syndrome (AIS)
new test:
ACAN Dwarfism (Chondrodysplasia)
new test:
Predictive Height Test ( LCORL)
new test:

Tractability
new test:
Coat colour Sunshire Dilution



See also:
Coat Colour: B Locus (bd, bc, bs) Brown Coat Colour  
T-Locus Ticking ( Roan, Mottle, Spotted )  
Coat Colours: D-Locus D1 ( Dilution )  
Coat Colours: K- Locus  
Coat Colours: EM-Locus Melanistic Mask Allele (Em), E-Locus  
Curly Coat  
Furnishings and Improper Coat  
Coat Colour EG- Locus (domino, grizzle)  
Coat Colour: EH-locus (sable)  
Coat Colour: S-locus (piebald, spotted white)*  
Hairlessness  
Harlequin  
Saddle Tan  
Coat (hair) Length I  
Coat (hair) Length II  
C Locus (Albino, caL, OCA2)  
Coat Length I + II ( Long or Short Hair)  
Coat Colours: E-Locus E2 (Red / Yellow)  
M Locus * / Merle Gene / Dapple (merle / Cryptic Merle)  
Coat Colour DNA bundle: Loci A + B + D1 + E1 + I + K + S  
I - Locus (phaeomelanin intensity)  
Coat Colour: D3 - Locus ( Dilution )  
Shedding ( MC5R )  
Cocoa ( Brown / Chocolate ) in French Bulldog  
C-Locus (Albino) / Oculocutaneous Albinism Type 4 (OCA4)  
Coat Colour: B Locus (rare variants: b4, be and bh) Brown Coat Colour  
Coat Colours: E-Locus E1 (yellow, lemon, red, cream and appricot)  
E-Locus Special Colours ('eA', 'eG' and 'eH')(Hare-pid, Grizzle / Domino, Sable)  
Coat Colour: D- Locus ( Dilution ) rare variant D2 / D3  
Coat Colours: A-Locus Agouti ( fawn, sable, black and tan/tricolor, recessive black)  

 
 
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LABOKLIN GmbH & Co. KG
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© 2007 Laboklin (UK)
125 Northenden Road, Manchester, M33 3HF
Tel. 0161 282 3066