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LABOKLIN (UK)| Genetic Diseases | Dogs| Pug Dog Encephalitis (PDE) / Necrotizing Meningoencephalitis (NME)
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Pug Dog Encephalitis (PDE) / Necrotizing Meningoencephalitis (NME)

Test number: 8429 (this test number replaces the old 8244D)
Gene: PDE
Price: £ 48.00 (including VAT)
Breed
Pug .
Kennel Club
This test is part of the Official UK Kennel Club DNA Testing Scheme in Pug.

for UK registered dogs, Laboklin can send results of the tests which are part of the Official UK Kennel Club DNA testing scheme to the Kennel Club (KC) to be recorded and published as part of the Kennel Club scheme. Results will only be recorded and published by the KC if the result report includes the dog’s microchip or tattoo number along with either the dog’s registered name or registered number. Any test results that do not carry these identifying features will not be recorded by the Kennel Club.

In order to ensure that test results are sent to the Kennel Club, customers must also sign the declaration section on the order form to give Laboklin permission to do so.

important: When you sign the declaration, Laboklin will send the results to the KC on your behalf, and you do not need to send them to the KC yourself again to avoid unnecessary duplications.

The Disease
Pug dog encephalitis (PDE) also know as necrotizing meningoencephalitis (NME), is an inflammatory disorder of the central nervous system that is usually progressive and fatal, it is most commonly found in small dog breeds. Clinical Symptoms include seizures, depression, ataxia, abnormal gait and blindness.

PDE is an auto-immune disease which affects the central nervous system.

Clinical Signs
First symptoms usually appear at the age of six months to three years and include disorientation, instability and seizures. Affected dogs hold their head tilted to one side or shake their heads, they wobble, show an unsteady gait, stumble and fall. Some walk in circles without being able to stop or scratch the head in an attempt to release pressure and pain. Evenetually dementia and coma occur. Dogs with encephalitis die 3-6 months after the onset of symptoms.

Trait of Inheritance
the test result can be either N/N (Clear or non-carrier), N/PDE (Carrier of the mutation) or PDE/PDE (homozygous for the mutation) , however, this is not a diagnostic tests, it is a risk factor mutation, which means that dogs tested affected (PDE/PDE) for the mutation have a higher risk of developing the disease although they may not develop the disease. Clear and carrier dogs have lower risk.

Inheritance : AUTOSOMAL trait
Sample Requirements
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.
Turnaround
2 - 3 weeks
Price
£ 48.00 (including VAT)

To order:




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