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**NEW**



Bengal Special offer:
3 Bengal Specific DNA tests for just £60.00 incl VAT
Bengal DNA bundle (rdAc-PRA + b-PRA + PK-Def) 



British Special offer:
3 Breed Specific DNA tests for just £60.00 incl VAT
British Short / Long Hair DNA bundle (PKD + pd-PRA + ALS)



Burmese Special offer:
3 Breed Specific DNA tests for just £66.00 incl VAT
Burmese DNA bundle (Hypokalemia (BHK) + Head Defect + Gangliosidosis (GM2)



Birman Special offer:
4 Breed Specific DNA tests for just £66.00 incl VAT
Birma DNA bundle (PKD + pd-PRA + Hypotrichiose + MPS6)



Maine Coon Special offer:
3 Breed Specific DNA tests for just £60.00 incl VAT
Maine Coon DNA bundle (HCM1 + SMA + PK-Def)



Ragdoll Special offer:
4 Breed Specific DNA tests for just £60.00 incl VAT
Ragdoll DNA bundle (HCM1 + HCM3 + PKD + pd-PRA)



Norwegian Special offer:
3 Breed Specific DNA tests for just £60.00 incl VAT
Norwegian Forest DNA bundle (PK-Def + Amber + GSD4)



Feline Special Offer:
8 cat DNA tests for just £79.95 including VAT
HCM, HCR, GSD4, PKD, PRA, PK-Def., SMA, Blood Groups

new test: Cocoa (Chocolate / Brown ) in French Bulldog
new test: Stargardt disease ( STGD )  and  Copper storage disease - Copper toxicosis (CT) in Labrador Retriever
new test: Inflammatory Pulmonary Disease ( IPD ) in Rough and Smooth Collies
new test: Lafora Disease in Basset Hound, Beagle, Chihuahua, French Bulldog, Welsh Corgi and Mini Wirehaired Dachshund
new Kennel Club DNA testing schemes with LABOKLIN:
• Pug Dog Encephalitis (PDE) / Necrotizing Meningoencephalitis (NME) in Pug
• Progressive Retinal Atrophy (prcd-PRA) and • Progressive retinal atrophy ( rcd4-PRA) / LOPRA in Standard Poodle
• Dwarfism ( Chondrodysplasia / disproportinate short-limbed ) and • Primary Open Angle Glaucoma (POAG) in Norwegian Elkhounds


Shedding ( MC5R )

Test number: 8403
Gene: MC5R
Breed
All Dog Breeds .
Description

The dogs coat structure and length are influenced by several known genetic traits. A variant in the MC5R gene has been found to be associated with hair shedding as well as the coat length.

The recessive allele for shedding (sh-allele) is found in breeds which tend to have high degree of shedding (genotype sh/sh). Dogs with one copy of the normal allele N-allele for non-shedding shed significantly less hair.

N/N: low shedding
N/sh: Moderate
sh/sh: High degree of shedding

The furnishing variant of the RSPO2 gene influences the shedding too. Dogs which are homozygous for the dominant furnishing genotype F/F do not show heavy shedding, irrespective of the genotype on the MC5R gene.

Coat length is determined by several recessive variants on the FGF5 gene (coat length locus) as well as the dominant furnishing variant on the RSPO2 gene. Additionally, the shedding gene is found to have influence on the coat length too.

Longer coat is generally associated with the recessive l-allele (long-haired), the dominant F-allele (furnished) and / or the recessive sh-allele (shedding), while short hair is associated with the dominant L-allele (short-haired), the recessive f-allele (unfurnished) and / or the dominant N-allele (non-shedding).

Medium hair-length seen in some genetically short-haired (FGF5 L/L or L/l) and unfurnished breeds from the shepherd or retriever group may be explained by the shedding gene.

 
Further reading
The Shedding GenePDF file
Shedding chartHTML file
Sample Requirements
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal swabs. .
Turnaround
1-3 weeks
Price
Number of Coat Colour Tests on the same dog Price (including VAT)
First Colour test £ 48.00
Each additional colour test on the same dog £ 24.00

To order:

  • Download Order Form from this link pdf

  • Complete the order form and send it together with your samples to the following address:

    Laboklin (UK),   125 Northenden Road, Manchester, M33 3HF




new test:
Androgen Insensitivity Syndrome (AIS)
new test:
ACAN Dwarfism (Chondrodysplasia)
new test:
Predictive Height Test ( LCORL)
new test:

Tractability
new test:
Coat colour Sunshire Dilution



See also:
Coat Colour: B Locus (bd, bc, bs) Brown Coat Colour  
Coat Length I + II ( Long or Short Hair)  
Coat Colours: D-Locus D1 ( Dilution )  
Coat Colours: K- Locus  
Coat Colours: EM-Locus Melanistic Mask Allele (Em), E-Locus  
Curly Coat  
Furnishings  
Coat Colour EG- Locus (domino, grizzle)  
Coat Colour: EH-locus (sable)  
Coat Colour: S-locus (piebald, spotted white)*  
Hairlessness  
Harlequin  
Saddle Tan  
Coat (hair) Length I  
Coat (hair) Length II  
Panda White Spotting  
C Locus (Albino, caL, OCA2)  
Coat Colours: E-Locus E2 (Red / Yellow)  
M Locus * / Merle Gene / Dapple (merle / Cryptic Merle)  
Coat Colour DNA bundle: Loci A + B + D1 + E1 + I + K + S  
I - Locus (phaeomelanin intensity)  
Coat Colour: D3 - Locus ( Dilution )  
Cocoa ( Brown / Chocolate ) in French Bulldog  
C-Locus (Albino) / Oculocutaneous Albinism Type 4 (OCA4)  
Coat Colour: B Locus (rare variants: b4, be and bh) Brown Coat Colour  
Coat Colours: E-Locus E1 (yellow, lemon, red, cream and appricot)  
E-Locus Special Colours ('eA', 'eG' and 'eH')(Hare-pid, Grizzle / Domino, Sable)  
Coat Colour: D- Locus ( Dilution ) rare variant D2 / D3  
T-Locus Ticking ( Roan, Mottle, Spotted )  
Improper Coat (IC) in PWD  
Coat Colours: A-Locus Agouti ( fawn, sable, black and tan/tricolor, recessive black)  

 
 
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LABOKLIN GmbH & Co. KG
ISO / DIN 17025 Accredited Laboratory
© 2007 Laboklin (UK)
125 Northenden Road, Manchester, M33 3HF
Tel. 0161 282 3066