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**NEW**



Bengal Special offer:
3 Bengal Specific DNA tests for just £60.00 incl VAT
Bengal DNA bundle (rdAc-PRA + b-PRA + PK-Def) 



British Special offer:
3 Breed Specific DNA tests for just £60.00 incl VAT
British Short / Long Hair DNA bundle (PKD + pd-PRA + ALS)



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Birman Special offer:
4 Breed Specific DNA tests for just £66.00 incl VAT
Birma DNA bundle (PKD + pd-PRA + Hypotrichiose + MPS6)



Maine Coon Special offer:
3 Breed Specific DNA tests for just £60.00 incl VAT
Maine Coon DNA bundle (HCM1 + SMA + PK-Def)



Ragdoll Special offer:
4 Breed Specific DNA tests for just £60.00 incl VAT
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Norwegian Special offer:
3 Breed Specific DNA tests for just £60.00 incl VAT
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Feline Special Offer:
8 cat DNA tests for just £79.95 including VAT
HCM, HCR, GSD4, PKD, PRA, PK-Def., SMA, Blood Groups

new test: Cocoa (Chocolate / Brown ) in French Bulldog
new test: Stargardt disease ( STGD )  and  Copper storage disease - Copper toxicosis (CT) in Labrador Retriever
new test: Inflammatory Pulmonary Disease ( IPD ) in Rough and Smooth Collies
new test: Lafora Disease in Basset Hound, Beagle, Chihuahua, French Bulldog, Welsh Corgi and Mini Wirehaired Dachshund
new Kennel Club DNA testing schemes with LABOKLIN:
• Pug Dog Encephalitis (PDE) / Necrotizing Meningoencephalitis (NME) in Pug
• Progressive Retinal Atrophy (prcd-PRA) and • Progressive retinal atrophy ( rcd4-PRA) / LOPRA in Standard Poodle
• Dwarfism ( Chondrodysplasia / disproportinate short-limbed ) and • Primary Open Angle Glaucoma (POAG) in Norwegian Elkhounds


Harlequin

Test number: 8254
Gene: H
Breed
Great Dane .
Description

The Harlequin coat colour pattern is a white coat colour with irregular patches of black or other dark colour.

The Harlequin gene does not cause the Harlequin pattern without the merle gene.

A Harlquin Great Dane must have both the Harlequin gene and the Merle gene.

Harlequin is a merle modifier, it turns the areas between the dark patches into white, this is why Harlequin is only visible on dogs with the merle gene.

Harlequin will not affect the coat colour of dogs that don't have the merle gene. Dogs without the merle gene can have the Harlequin gene but without expressing it.

If the dog is double merle (M/M) the Harlequin gene effect may not be noticeable.

The harlequin gene is dominant which means that only one copy of the gene is enough to express the Harlequin pattern in merle dogs.

Dogs with two copies of the Harlequin gene H/H will very likley die during gestation and will be reabsorbed into the womb, therefore breeding Harlequin (H/h) to Harlequin (H/h) may result in smaller litter size.

Result interpretation:

h/h (No Harlequin): the dog does not carry the Harlequin gene, the dog will pass the h allele to its entire offspring.

H/h (Carrier): The dog carries one copy of the dominant Harlequin allele H which results in the expression of the Harlequin pattern only in dogs with one (M/m) or two (M/M) copies of the merle allele at the M locus.(Please note that Harlequin expression in M/M dogs at the M locus may not apparent)

H/H: Embryonic Lethal, dogs with H/H die before birth.

Please note that the merle pattern is not expressed in dogs with Pheomelanin coat colours (Red, fawn, Sable, Cream) so you cannot tell if the dog carries the merle gene or not, However, if the dog is H/h, the harlequin pattern will be expressed, this is known as "fawnequin".

Sample Requirements
Buccal Swabs or 0.5 - 1 ml blood in EDTA Blood Tube
Buccal swabs or 0.5 - 1 ml blood in EDTA Blood Tube .
Turnaround
2 - 3 weeks
Price
Number of Coat Colour Tests on the same dog Price (including VAT)
First Colour test £ 48.00
Each additional colour test on the same dog £ 24.00

To order:

  • Download Order Form from this link pdf

  • Complete the order form and send it together with your samples to the following address:

    Laboklin (UK),   125 Northenden Road, Manchester, M33 3HF




new test:
Androgen Insensitivity Syndrome (AIS)
new test:
ACAN Dwarfism (Chondrodysplasia)
new test:
Predictive Height Test ( LCORL)
new test:

Tractability
new test:
Coat colour Sunshire Dilution



See also:
Coat Colour: B Locus (bd, bc, bs) Brown Coat Colour  
T-Locus Ticking ( Roan, Mottle, Spotted )  
Coat Colours: D-Locus D1 ( Dilution )  
Coat Colours: K- Locus  
Coat Colours: EM-Locus Melanistic Mask Allele (Em), E-Locus  
Curly Coat  
Furnishings and Improper Coat  
Coat Colour EG- Locus (domino, grizzle)  
Coat Colour: EH-locus (sable)  
Coat Colour: S-locus (piebald, spotted white)*  
Hairlessness  
Saddle Tan  
Coat (hair) Length I  
Coat (hair) Length II  
Panda White Spotting  
C Locus (Albino, caL, OCA2)  
Coat Length I + II ( Long or Short Hair)  
Coat Colours: E-Locus E2 (Red / Yellow)  
M Locus * / Merle Gene / Dapple (merle / Cryptic Merle)  
Coat Colour DNA bundle: Loci A + B + D1 + E1 + I + K + S  
I - Locus (phaeomelanin intensity)  
Coat Colour: D3 - Locus ( Dilution )  
Shedding ( MC5R )  
Cocoa ( Brown / Chocolate ) in French Bulldog  
C-Locus (Albino) / Oculocutaneous Albinism Type 4 (OCA4)  
Coat Colour: B Locus (rare variants: b4, be and bh) Brown Coat Colour  
Coat Colours: E-Locus E1 (yellow, lemon, red, cream and appricot)  
E-Locus Special Colours ('eA', 'eG' and 'eH')(Hare-pid, Grizzle / Domino, Sable)  
Coat Colour: D- Locus ( Dilution ) rare variant D2 / D3  
Coat Colours: A-Locus Agouti ( fawn, sable, black and tan/tricolor, recessive black)  

 
 
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LABOKLIN GmbH & Co. KG
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© 2007 Laboklin (UK)
125 Northenden Road, Manchester, M33 3HF
Tel. 0161 282 3066