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LABOKLIN (UK)| Coat Colours / Length | Horses| Greying
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**NEW**



Maine Coon Special offer:
8 DNA tests for just £84.95 incl VAT
Maine Coon 8 DNA tests bundle (HCM, SMA, PKDef, Poly, b, b1, cb, cs) 
**NEW**



Bengal Special offer:
4 Bengal Specific DNA tests for just £72.00 incl VAT
Bengal DNA bundle (rdAc-PRA + b-PRA + PK-Def + Blood Groups) 



British Special offer:
4 Breed Specific DNA tests for just £72.00 incl VAT
British Short / Long Hair DNA bundle (PKD + pd-PRA + ALS + Blood Groups)



Burmese Special offer:
4 Breed Specific DNA tests for just £72.00 incl VAT
Burmese DNA bundle (Hypokalemia (BHK) + Head Defect + Gangliosidosis (GM2) + Blood Groups



Birman Special offer:
5 Breed Specific DNA tests for just £72.00 incl VAT
Birma DNA bundle (PKD + pd-PRA + Hypotrichiose + MPS6 + Blood Groups)



Maine Coon Special offer:
5 Breed Specific DNA tests for just £72.00 incl VAT
Maine Coon DNA bundle (HCM1 + SMA + PK-Def + F11 + Blood Groups)



Ragdoll Special offer:
5 Breed Specific DNA tests for just £72.00 incl VAT
Ragdoll DNA bundle (HCM1 + HCM3 + PKD + pd-PRA + Blood Groups)



Norwegian Special offer:
4 Breed Specific DNA tests for just £72.00 incl VAT
Norwegian Forest DNA bundle (PK-Def + Amber + GSD4 + Blood Groups)



Feline Special Offer:
8 cat DNA tests for just £84.95 including VAT
HCM, HCR, GSD4, PKD, PRA, PK-Def., SMA, Blood Groups

new test:      Paradoxical Pseudomyotonia (PP) in English Cocker and English Springer Spaniels  
new test:      Dyserythropoietic Anemia and Myopathy Syndrome (DAMS) in English Springer Spaniel
new test:      Lysosomal Storage Diseases (LSD) in Dalmatian and Doberman  
new Kennel Club DNA testing schemes with LABOKLIN:
   Osteochondrodysplasia (OCD) / Skeletal Dwarfism in Miniature Poodles
  DINGS2: Deafness with Vestibular Dysfunction in Doberman
   Dyserythropoietic Anemia and Myopathy Syndrome (DAMS) in English Springer Spaniel


Greying

Test number: 8159 (this test number replaces the old 8159H)
Gene: G
Price: £ 66.00 (including VAT)
Breed
All Horse Breeds .
The Disease
Horses with the mutation causing Graying are born colored but gradually lose hair pigmentation and become white by the age of 6-9 years. Gray horses show a very high incidence of dermal melanomas and reduced longevity. The loss of hair pigmentation in Gray horses is fully dominant whereas the speed of Graying and the incidence of melanoma is increased in homozygous animals.

The gray gene does not affect skin or eye color, so grays typically have dark skin and eyes, as opposed to the unpigmented pink skin of white horses.

Trait of Inheritance
The gray gene (G) is an autosomal dominant gene, therefore, a horse which has only one copy of the gray allele, even if it has a gene for another coloring, will always become gray. If a gray horse is homozygous (GG), meaning that it has a gray allele from both parents, it will always produce gray offspring. However, if a gray horse is heterozygous (Gg), meaning it inherits one copy of the recessive gene (g), that animal may produce offspring who are not gray (depending on what color gene an offspring inherits from its other parent). A gray horse must have at least one gray parent. It is now possible to determine whether a horse is homozygous or heterozygous for gray ot if the horse does not carry the gene at all. this is useful to know whether a non gray foal will become gray or not and since, graying is associated with the development of melanoma, this test is particularly useful. Gray is controlled by a single dominant allele of a gene that regulates specific kinds of stem cells. The identification of the gray mutation is also of great interest in of medical research since this mutation also enhances the risk for melanoma in horses; About 75% of grey horses over 15 years of age have a benign form of melanoma that in some cases develops into a malignant melanoma

Inheritance : AUTOSOMAL DOMINANT trait
Sample Requirements
Hair Sample from mane with roots (approx 30 hairs) , Buccal Swabs or 1 ml whole blood in EDTA tube.

How to obtain a viable hair sample

Pull around 30 hairs from the mane of the horse with the roots (in faols hair from the tail maybe taken). Wrap the hairs around your finger or a comb, as close as possible to the skin to ensure you obtain the hair roots. Keep dry, put in a bag, label the bag with the horse name, test (s) required. Place in an envelope and send back to us together with the order form. Broken or cut off hair will not be accepted.

Turnaround
4 - 5 weeks
Price
£ 66.00 (including VAT)

To order:




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See also:

 
 
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