Nannizziopsis spp.

Keratinophilic fungi of the genus Nannizziopsis (N.) spp., order Onygenales, are known to cause a variety of skin alterations especially in lizards. The most common pathogen of this genus is Nannizziopsis guarroi.

There are several other known species, like N. dermatitidis, N. chlamydospora, N. vriesii, N. crocodili und N. barbatae. Infections have been described worldwide and can be present in wild as well as captive animals. Central bearded dragons (Pogona vitticeps) are the most frequently affected lizard species, however, it can also be present in other reptiles. Infected animals commonly develop ulcerative or scabby dermatitis. Yellow discolourations are possible, for which the disease had been called “yellow fungus disease” in the past. Granulomas are common. Infections range from mild to severe, and can also affect internal organs. If left untreated, chronic infections develop progressively and can lead to the death of the animal. Transmission occurs via direct contact, but indirect transmission via the environment might also be possible.

Nannizziopsis can cause skin disease in reptiles, which can progress to systemic and sometimes fatal disease.

The skin lesions associated with this disease were previously referred to as 'yellow fungus disease'.

Nannizziopsis spp. Infections have been reported in various lizard species, such as chameleons, geckos, dragon and iguana lizards, and crocodiles.