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Osteochondrodysplasia (OCD) / Skeletal Dwarfism in Miniature Poodles
Test number: 8877
Gene: OCD
Price: £ 48.00 (including VAT)
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Kennel Club
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This test is part of the Official UK Kennel Club DNA Testing Scheme in Miniature Poodle.
for UK registered dogs, Laboklin can send results of the tests which are part of the Official UK Kennel Club DNA testing scheme to the Kennel Club (KC) to be recorded and published
as part of the Kennel Club scheme. Results will only be recorded and published by the KC if the result report includes the dog’s
microchip or tattoo number along with either the dog’s registered name or registered number. Any test results that do not carry these identifying
features will not be recorded by the Kennel Club.
In order to ensure that test results are sent to the Kennel Club, customers must also sign the declaration section on the order form to give Laboklin permission to do so.
important:
When you sign the declaration, Laboklin will send the results to the KC on your behalf, and you do not need to send them to the KC yourself again to avoid unnecessary duplications.
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The Disease |
Osteochondrodysplasia (OCD) / Skeletal Dwarfism in Miniature Poodles
Osteochondrodysplasia is an inherited disease of the skeletal muscles affecting the Miniature Poodle breed. OCD is characterized by stunted growth at around 3 weeks of age. Affected puppies and abnormal locomotion and often walk differently compared with their healthy littermates. Affected animals develop splayed hind limbs, enlarged joints, flattened rib cages, the long bones are bent and shorter, and the paws can have deformity. Affected animals develop underbites, which can affect their ability to nurse and breathe. Dogs that are affected can survive for many years with supportive care. However, they will develop arthritis and may experience breathing difficulties due to the deformity in the ribcages.
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Trait of Inheritance |
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OCD has an autosomal recessive trait of inheritance
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Inheritance : AUTOSOMAL
RECESSIVE
trait
Sire
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Dam
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Offspring
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clear
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clear
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100% clear
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clear
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carrier
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50% clear + 50%
carriers
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clear
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affected
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100% carriers
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carrier
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clear
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50% clear + 50%
carriers
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carrier
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carrier
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25% clear + 25% affected
+ 50% carriers
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carrier
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affected
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50% carriers + 50%
affected
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affected
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clear
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100% carriers
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affected
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carrier
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50% carriers + 50%
affected
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affected
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affected
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100% affected
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Clear
Genotype: N / N [ Homozygous normal ]
The dog is noncarrier of the mutant gene.
It is very unlikely that the dog will develop Osteochondrodysplasia (OCD) / Skeletal Dwarfism in Miniature Poodles. The dog will never pass the mutation to its offspring, and therefore it can be bred to any other dog.
Carrier
Genotype: N / OCD [ Heterozygous ]
The dog carries one copy of the mutant gene and one
copy of the normal gene.
It is very unlikely that the dog will develop Osteochondrodysplasia (OCD) / Skeletal Dwarfism in Miniature Poodles but since it carries the mutant gene, it can pass it on to its offspring with the probability of 50%. Carriers should only be bred to clear dogs. Avoid breeding carrier to carrier because 25% of their offspring is expected to be affected (see table above)
Affected
Genotype: OCD / OCD [ Homozygous mutant ]
The dog carries two copies of the mutant gene and
therefore it will pass the mutant gene to its entire offspring.
The dog is likely to develop Osteochondrodysplasia (OCD) / Skeletal Dwarfism in Miniature Poodles and will pass the mutant gene to its entire offspring
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Price
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£ 48.00 (including VAT)
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