Cockapoo (English) , English Cocker Spaniel , English Pointer , English Springer Spaniel , French Spaniel , German Shorthair Pointer .

This test is part of the Official UK Kennel Club DNA Testing Scheme in English Cocker Spaniel, and English Springer Spaniel.

for UK registered dogs, Laboklin can send results of the tests which are part of the Official UK Kennel Club DNA testing scheme to the Kennel Club (KC) to be recorded and published as part of the Kennel Club scheme. Results will only be recorded and published by the KC if the result report includes the dog’s microchip or tattoo number along with either the dog’s registered name or registered number. Any test results that do not carry these identifying features will not be recorded by the Kennel Club.

In order to ensure that test results are sent to the Kennel Club, customers must also sign the declaration section on the order form to give Laboklin permission to do so.

important: When you sign the declaration, Laboklin will send the results to the KC on your behalf, and you do not need to send them to the KC yourself again to avoid unnecessary duplications.

Recessive trait of inheritance, which means that a dog must inherit two copies of the mutation (one from each parent) to become genetically affected.

Sire		Dam		Offspring
clear		clear		100% clear
clear		carrier		50%  clear + 50% carriers
clear		affected		100% carriers
carrier		clear		50%  clear + 50% carriers
carrier		carrier		25% clear + 25% affected + 50% carriers
carrier		affected		50% carriers + 50% affected
affected		clear		100%  carriers
affected		carrier		50% carriers + 50% affected
affected		affected		100% affected

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.

1-2 weeks

Airedale Terrier , Alaskan Malamute , All Dog Breeds , American Eskimo , Bernese Mountain Dog , Bloodhound , Borzoi (Russian Wolfhound) , Boxer , Cavalier King Charles Spaniel , Canaan Dog , Welsh Corgi (Cardigan) , Chesapeake Bay Retriever , Cockapoo (English) , Cockapoo (American) , Fox Terrier , French Bull Dog , German Shepherd , Glen Of Imaal Terrier ( GIT ) , Golden Retriever , Goldendoodle , Pyrenean Mountain Dog (Great Pyrenees) , Hovawart , Pumi ( Hungarian Pumi / Pumik ) , Jack Russell Terrier , Kerry Blue Terrier , Labradoodle , Labrador Retriever , Lakeland Terrier , Northern Inuit (Tamaskan / British Timber Dog) , Nova Scotia Duck tolling Retriever ( NSDTR / Toller) , Pembroke Welsh Corgi , Poodle , Pug , Rhodesian Ridgeback , Rough Collie , Soft Coated Wheaten Terrier , Shetland Sheepdog (Sheltie) , Smooth Collie , Utonagan , Wire Fox Terrier .

This test is part of the Official UK Kennel Club DNA Testing Scheme in Chesapeake Bay Retriever, French Bull Dog, German Shepherd, Nova Scotia Duck tolling Retriever ( NSDTR / Toller), Rough Collie, and Smooth Collie.

for UK registered dogs, Laboklin can send results of the tests which are part of the Official UK Kennel Club DNA testing scheme to the Kennel Club (KC) to be recorded and published as part of the Kennel Club scheme. Results will only be recorded and published by the KC if the result report includes the dog’s microchip or tattoo number along with either the dog’s registered name or registered number. Any test results that do not carry these identifying features will not be recorded by the Kennel Club.

In order to ensure that test results are sent to the Kennel Club, customers must also sign the declaration section on the order form to give Laboklin permission to do so.

important: When you sign the declaration, Laboklin will send the results to the KC on your behalf, and you do not need to send them to the KC yourself again to avoid unnecessary duplications.

Degenerative myelopathy initially affects the back legs and causes muscle weakness and loss, and lack of coordination. These cause a staggering effect that may appear to be arthritis. The dog may drag one or both rear paws when it walks. This dragging can cause the nails of one foot to be worn down. The condition may lead to extensive paralysis of the back legs. As the disease progresses, the animal may display symptoms such as incontinence and has considerable difficulties with both balance and walking. If allowed to progress, the animal will show front limb involvement and extensive muscle atrophy. Eventually cranial nerve or respiratory muscle involvement necessitates euthanasia. Progression of the disease is generally slow but highly variable. The animal could be crippled within a few months, or may survive up to three years

Tow alleles are invloved in Degenerative Myelopathy, A and G, therefore a test result can be A/A, A/G, or G/G.

Mode of inheritance is autosomal recessive with variable penetrance;

Sire		Dam		Offspring
clear		clear		100% clear
clear		carrier		50%  clear + 50% carriers
clear		affected		100% carriers
carrier		clear		50%  clear + 50% carriers
carrier		carrier		25% clear + 25% affected + 50% carriers
carrier		affected		50% carriers + 50% affected
affected		clear		100%  carriers
affected		carrier		50% carriers + 50% affected
affected		affected		100% affected

Buccal Swabs or 0.5 - 1 ml blood in EDTA Blood Tube

1 - 2 weeks

Cockapoo (English) , English Cocker Spaniel , Welsh Springer Spaniel .

This test is part of the Official UK Kennel Club DNA Testing Scheme in English Cocker Spaniel.

for UK registered dogs, Laboklin can send results of the tests which are part of the Official UK Kennel Club DNA testing scheme to the Kennel Club (KC) to be recorded and published as part of the Kennel Club scheme. Results will only be recorded and published by the KC if the result report includes the dog’s microchip or tattoo number along with either the dog’s registered name or registered number. Any test results that do not carry these identifying features will not be recorded by the Kennel Club.

In order to ensure that test results are sent to the Kennel Club, customers must also sign the declaration section on the order form to give Laboklin permission to do so.

important: When you sign the declaration, Laboklin will send the results to the KC on your behalf, and you do not need to send them to the KC yourself again to avoid unnecessary duplications.

FN in English Cocker Spaniel is caused by a type IV collagen defect, which can be detected by a mutation-based gene test. FN is inherited as an autosomal recessive trait. So there are three conditions a dog can be: it can be clear (genotype N/N or homozygous normal) meaning that it does not carry the mutation and will not develop FN. Since it also cannot pass the mutation onto its offspring, it can be mated to any other dog. A dog which has one copy of the gene with the mutation and one copy without the mutation is called a carrier or heterozygous (genotype N/FN); while it will not be affected by FN, it can pass the mutation onto its offspring and should therefore only be mated to clear dogs. Dogs that develop FN have two gene copies with the mutation (genotype FN/FN or homozygous affected); they will always pass the mutated gene onto their offspring and should also be mated only to clear dogs.

Sire		Dam		Offspring
clear		clear		100% clear
clear		carrier		50%  clear + 50% carriers
clear		affected		100% carriers
carrier		clear		50%  clear + 50% carriers
carrier		carrier		25% clear + 25% affected + 50% carriers
carrier		affected		50% carriers + 50% affected
affected		clear		100%  carriers
affected		carrier		50% carriers + 50% affected
affected		affected		100% affected

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.

1 - 2 weeks

All Dog Breeds , American Cocker Spaniel , American Eskimo , Australian Cattle Dog , Australian Shepherd , Australian Stumpy Tail Cattle Dog , Australian Stumpy tail cattle Dog , Barbet (French Water Dog) , Bearded Collie , Bolognese , Bolonka Zwetna (Tsvetnaya Bolonki) , Cavapoo , Chesapeake Bay Retriever , Chihuahua , Chinese Crested , Cockapoo (English) , Cockapoo (American) , Cocker Spaniel , Dwarf poodle , English Cocker Spaniel , English shepherd , Entlebuch Mountain dog , Finnish Lapphund , German Spitz (Mittel) , Giant Schnauzer , Golden Retriever , Goldendoodle , Jack Russell Terrier , Japanese Chin , Karelian Bear Dog , Kuvasz , Labradoodle , Labrador Retriever , Lagotto Romagnolo , Lapponian Herder , Markiesje , Miniature Poodle , Miniature American Shepherd , Norwegian Elkhound , Nova Scotia Duck tolling Retriever ( NSDTR / Toller) , Parson Russell Terrier (PRT) , Poodle , Portuguese Waterdog , Schipperke , Australian Silky Terrier , Spanish Water Dog , Standard Poodle , Swedish Lapp Hund , Toy Poodle , Waeller (Wäller) , Yorkshire Terrier .

This test is part of the Official UK Kennel Club DNA Testing Scheme in American Cocker Spaniel, Australian Cattle Dog, Australian Shepherd, Barbet (French Water Dog), Chesapeake Bay Retriever, Chinese Crested, Cocker Spaniel, English Cocker Spaniel, Entlebuch Mountain dog, Finnish Lapphund, Giant Schnauzer, Labrador Retriever, Miniature Poodle, Norwegian Elkhound, Nova Scotia Duck tolling Retriever ( NSDTR / Toller), Portuguese Waterdog, Spanish Water Dog, Standard Poodle, and Toy Poodle.

for UK registered dogs, Laboklin can send results of the tests which are part of the Official UK Kennel Club DNA testing scheme to the Kennel Club (KC) to be recorded and published as part of the Kennel Club scheme. Results will only be recorded and published by the KC if the result report includes the dog’s microchip or tattoo number along with either the dog’s registered name or registered number. Any test results that do not carry these identifying features will not be recorded by the Kennel Club.

In order to ensure that test results are sent to the Kennel Club, customers must also sign the declaration section on the order form to give Laboklin permission to do so.

important: When you sign the declaration, Laboklin will send the results to the KC on your behalf, and you do not need to send them to the KC yourself again to avoid unnecessary duplications.

The mutation in the PRCD gene which has been suggested to cause prcd-PRA has recently been published by the group of Gustavo D. Aguirre at the University of Pennsylvania, USA, and could be found in several dog breeds. Prcd-PRA is inherited as an autosomal recessive trait. So there are three conditions a dog can be: it can be clear (genotype N/N or homozygous normal) meaning that it does not carry the mutation and will not develop the prcd-form of PRA. Since it also cannot pass the mutation onto its offspring, it can be mated to any other dog.

A dog which has one copy of the PRCD gene with the mutation and one copy without the mutation is called a carrier or heterozygous (genotype N/PRA); while it will not be affected by prcd-PRA, it can pass the mutation onto its offspring and should therefore only be mated to clear dogs. Dogs that develop this form of PRA have two PRCD gene copies with the mutation (genotype PRA/PRA or homozygous affected); they will always pass the mutated gene onto their offspring and should also be mated only to clear dogs..

Sire		Dam		Offspring
clear		clear		100% clear
clear		carrier		50%  clear + 50% carriers
clear		affected		100% carriers
carrier		clear		50%  clear + 50% carriers
carrier		carrier		25% clear + 25% affected + 50% carriers
carrier		affected		50% carriers + 50% affected
affected		clear		100%  carriers
affected		carrier		50% carriers + 50% affected
affected		affected		100% affected

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.

2 - 3 weeks

Barbet (French Water Dog) , Bernese Mountain Dog , Cavapoo , Cockapoo (English) , Cockapoo (American) , Coton de Tulear , Doberman Pinscher , Drentsche Patrijschond , English Toy Terrier , German Pinscher , Goldendoodle , Irish Red and White Setter , Irish Setter (Red Setter) , Kerry Blue Terrier , Kromfohrländer , Labradoodle , Manchester Terrier , Miniature Poodle , Papillon (Continental Toy Spaniel ) , Pembroke Welsh Corgi , Poodle , Stabyhound ( Stabijhoun ) , Standard Poodle , Toy Poodle .

This test is part of the Official UK Kennel Club DNA Testing Scheme in Doberman Pinscher, Manchester Terrier, Papillon (Continental Toy Spaniel ), and Standard Poodle.

for UK registered dogs, Laboklin can send results of the tests which are part of the Official UK Kennel Club DNA testing scheme to the Kennel Club (KC) to be recorded and published as part of the Kennel Club scheme. Results will only be recorded and published by the KC if the result report includes the dog’s microchip or tattoo number along with either the dog’s registered name or registered number. Any test results that do not carry these identifying features will not be recorded by the Kennel Club.

In order to ensure that test results are sent to the Kennel Club, customers must also sign the declaration section on the order form to give Laboklin permission to do so.

important: When you sign the declaration, Laboklin will send the results to the KC on your behalf, and you do not need to send them to the KC yourself again to avoid unnecessary duplications.

Symptoms include spontaneous bleeding from the nose, gum and other mucous membranes. Excessive bleeding occurs after an injury, trauma or a surgery. Often dogs don’t show clinical signs until something starts the bleeding, such as nail trimming, teething, spaying, sterilizing, tail docking, cropping or other causes. Bleeding also occurs internally in the stomach, intestines, urinary tracts, the genitals and / or into the joints.

Type I von Willebrand's disease is considered relatively mild when compared to Type II in Scotch Terriers and Shetland Sheep Dogs and Type III in the German Wirehaired pointer, Type II and Type III are much more severe than type I.

vWD Type I is transmitted as autosomal incomplete dominant trait . This means that a dog that is genetically clear (also called homozygous normal) will not develop the vWD disorder and will not pass it to its offspring. Carrier dogs which carries one copy of the abnormal gene and another normal copy (also known as heterozygous) will have bleeding tendency. These carrier dogs will pass the abnormal gene to their offspring with a probability of 50%, the trait is called incomplete dominance because carrier dogs may not develop the disorder at all but they will still pass the abnormal gene to their offspring. Because it is very uncommon for carriers to show symptoms of vWD this condition is treated as Recessive. Affected dogs (carry two copies of the abnormal gene) will develop the vWD disorder and will pass the abnormal gene to each of their offspring

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.

1 - 2 weeks

Goldendoodle , Standard Poodle .

Autosomal recessive trait

Sire		Dam		Offspring
clear		clear		100% clear
clear		carrier		50%  clear + 50% carriers
clear		affected		100% carriers
carrier		clear		50%  clear + 50% carriers
carrier		carrier		25% clear + 25% affected + 50% carriers
carrier		affected		50% carriers + 50% affected
affected		clear		100%  carriers
affected		carrier		50% carriers + 50% affected
affected		affected		100% affected

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.

2 - 3 weeks

Australian Cattle Dog , Cavapoo , Cockapoo (English) , Cockapoo (American) , Dwarf poodle , English Setter , Gordon Setter , Irish Red and White Setter , Irish Setter (Red Setter) , Labradoodle , Miniature Poodle , Old Danish Pointing Dog , Polish Lowland sheepdog , Poodle , Small Munsterlander , Standard Poodle , Tatra Shepherd Dog (POP) , Tibetan Terrier , Toy Poodle .

This test is part of the Official UK Kennel Club DNA Testing Scheme in English Setter, Gordon Setter, Irish Setter (Red Setter), Standard Poodle, and Tibetan Terrier.

for UK registered dogs, Laboklin can send results of the tests which are part of the Official UK Kennel Club DNA testing scheme to the Kennel Club (KC) to be recorded and published as part of the Kennel Club scheme. Results will only be recorded and published by the KC if the result report includes the dog’s microchip or tattoo number along with either the dog’s registered name or registered number. Any test results that do not carry these identifying features will not be recorded by the Kennel Club.

In order to ensure that test results are sent to the Kennel Club, customers must also sign the declaration section on the order form to give Laboklin permission to do so.

important: When you sign the declaration, Laboklin will send the results to the KC on your behalf, and you do not need to send them to the KC yourself again to avoid unnecessary duplications.

Autosomal recessive

Sire		Dam		Offspring
clear		clear		100% clear
clear		carrier		50%  clear + 50% carriers
clear		affected		100% carriers
carrier		clear		50%  clear + 50% carriers
carrier		carrier		25% clear + 25% affected + 50% carriers
carrier		affected		50% carriers + 50% affected
affected		clear		100%  carriers
affected		carrier		50% carriers + 50% affected
affected		affected		100% affected

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.

2 - 3 weeks

£ 180.00 (including VAT)