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XL - PRA (Progressive retinal Atrophy)
Test number: 8608
Gene: XL - PRA
Price: £ 48.00 (including VAT)
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Breeds
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Samoyed
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Siberian Husky
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Kennel Club
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This test is part of the Official UK Kennel Club DNA Testing Scheme in Samoyed.
for UK registered dogs, Laboklin can send results of the tests which are part of the Official UK Kennel Club DNA testing scheme to the Kennel Club (KC) to be recorded and published
as part of the Kennel Club scheme. Results will only be recorded and published by the KC if the result report includes the dog’s
microchip or tattoo number along with either the dog’s registered name or registered number. Any test results that do not carry these identifying
features will not be recorded by the Kennel Club.
In order to ensure that test results are sent to the Kennel Club, customers must also sign the declaration section on the order form to give Laboklin permission to do so.
important:
When you sign the declaration, Laboklin will send the results to the KC on your behalf, and you do not need to send them to the KC yourself again to avoid unnecessary duplications.
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The Disease |
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Normally, the vision receptors in the eyes undergo a continual process of replacement and renewal. But with PRA this process slows and, one day, stops. The night vision receptors are the first to fail, and then, a while later, day vision starts to degenerate.
XL-PRA is a "late-onset" form of PRA. It usually isn't until dogs are three to five years old that the first clinical signs of disease start to manifest
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Trait of Inheritance |
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Inheritance : X-LINKED
RECESSIVE
trait
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Sire |
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Dam |
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Offspring |
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Males |
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Females |
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clear
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clear
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100% clear
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100% clear
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clear
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carrier
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50% clear + 50%
affected
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50% clear + 50%
carriers
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clear
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affected
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100% affected
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100% carriers
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affected
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clear
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100% clear
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100% carriers
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affected
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carrier
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50% affected + 50% clear
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50% affected + 50%
carriers
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affected
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affected
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100% affected
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100% affected
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Male:
Clear
Genotype: N [ normal ]
The dog is noncarrier of the mutant gene.
The dog will never develop XL - PRA (Progressive retinal Atrophy) and therefore it can be used in breeding and should only be bred to clear females.
Affected
Genotype: XL - PRA [ mutant ]
The dog carries the mutant gene and will pass it its entire female offspring.
The dog will develop XL - PRA (Progressive retinal Atrophy) and will pass the mutant gene to its entire female offspring
Female:
Clear
Genotype: N / N [ Homozygous normal ]
The dog is noncarrier of the mutant gene.
The dog will never develop XL - PRA (Progressive retinal Atrophy) and therefore it can be used in breeding and should only be bred to clear females.
Carrier
Genotype: N / XL - PRA [ Heterozygous ]
The dog carries one copy of the mutant gene and one
copy of the normal gene.
The dog will never develop XL - PRA (Progressive retinal Atrophy) but since it carries the mutant gene, it can pass it on to its offspring.
Affected
Genotype: XL - PRA / XL - PRA [ Homozygous mutant ]
The dog carries two copies of the mutant gene and
therefore it will pass the mutant gene to its entire offspring.
The dog will develop XL - PRA (Progressive retinal Atrophy) and will pass the mutant gene to its entire female offspring
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Description |
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Normally, the vision receptors in the eyes undergo a continual process of replacement and renewal. But with PRA this process slows and, one day, stops. The night vision receptors are the first to fail, and then, a while later, day vision starts to degenerate.
XL-PRA is a "late-onset" form of PRA. It usually isn't until dogs are three to five years old that the first clinical signs of disease start to manifest
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Price
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£ 48.00 (including VAT)
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