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Lethal Lung Disease (LLD / LAMP3)
Test number: 8598
Gene Name: LAMP3
Short Name: LLD
Price: £ 48.00 (including VAT)
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The Disease |
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Lethal lung disease in new born Airedale Terrier dogs is a genetic disease caused by a recessive variant in the lysosome associated membrane LAMP3 gene. This genetic defect causes a defect in the maturation of the Surfactant producing organelle of the lung epithelium. Surfactants are mixture of lipids and proteins essential for life that form a thin surface lining film in the gas exchange compartment of the lungs, the alveolus. Surfactants reduces surface tension on the surface of these cells, essential to breathing. Surfactants are produced by the vacuoles which are closed sacs, made of membranes with inorganic or organic molecules inside, such as enzymes. In affected puppies the vacuoles don’t mature and therefore are unable to produce the surfactant causing lethal hypoxic respiratory distress and failure within the first days or weeks of life in affected puppies.
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Sample Requirements |
Whole blood in EDTA tube (0.5 - 1 ml) |
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Price
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£ 48.00 (including VAT)
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| To order:
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Download
Order Form from this link
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Complete the order form and send it together
with your samples to the following address:
Laboklin (UK), Unit 20, Wheel Forge Way, Trafford Park, Manchester, M17 1EH
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Buccal swabs and EDTA tubes are available from
us free of charge, to order, please use the
online form:
- If
you are sending swab samples, please follow the
instructions on this link .
- Download your copy of the Genetics Tests Catalogue from this link
Our catalogue includes a complete list of all available DNA tests, along with their corresponding test numbers.
- If you have any queries, please contact us on
0161 282 3066
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