In affected dogs, the Kidney's proximal tubules fail to reabsorb vitamins, minerals, sugars and other nutrients back into the body, instead they are dumped into the urine. The loss of these nutrients results in dehydration and electrolyte imbalances along with other problem.

Fanconi Syndrome is considered as one of the most common inherited disease in Basenji .

Symptoms include polydipsia (excessive drinking), polyuria (excessive urination), and glucose in the urine (glucosuria). Untreated Fanconi Syndrome will lead to muscle wasting, acidosis and poor condition, and eventually death.

The age of onset is typically between four and eight years of age, however, symptoms have been seen in dogs as young as two years old and as old as eleven years.

The disease is progressive. The progression rate is variable.

* test performed by partner lab