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Muscular Dystrophy (MD)
Test number: 8068 (this test number replaces the old 8068R)
Gene: MD
Price: £ 48.00 (including VAT)
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Breeds
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American Staffordshire Terrier
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Cavalier King Charles Spaniel
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Cavapoo
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Golden Retriever
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Goldendoodle
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Landseer
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Norfolk Terrier
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Trait of Inheritance |
- X-chromosomal recessive (Cavalier King Charles Spaniel, Golden Retriever, Norfolk Terrier)
- autosomal recessive (Landseer)
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Inheritance :
RECESSIVE
trait
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Description |
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PCR
Muscular dystrophy (MD) in Cavalier King Charles Spaniel, Golden Retriever and Norfolk Terrier is a spontaneous, X-linked, progressively fatal disease of dogs and is also a homologue of Duchenne muscular dystrophy (DMD). Affected dogs show raised creatine kinase levels, muscle atrophy with contractures, hyaline myofiber degeneration with mineralization, endomysial and perimysial fibrosis with fatty infiltration, and cardiomyopathy. In American Staffordshire Terrier and Landseer, Muscular Dystrophy is inherited as an autosomal recessive trait. Affected dogs exhibit a general, whole body muscular weakness, they move slowly and clumsy and some cannot walk at all. First symptoms in the course of movement appear at the age of three to six month. Affected dogs usualy die between the ages of 4 and 24 months.
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Price
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£ 48.00 (including VAT)
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