In puppies, however, severe courses of the disease with haemorrhagic gastroenteritis are possible. Loss of intestinal villi, flattening of the epithelial cells of the small intestine and detachment of the goblet cells occur. The most noticeable signs are vomiting and watery to bloody diarrhoea, accompanied by severe dehydration. The virus is excreted via the faeces; the duration of excretion is usually less than two weeks. CCV is also infectious to other canids as well as to cats and pigs, but the pathogenicity of these species is not yet known.