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Spanish Water Dog DNA bundle
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1 ) Brachyury (Bobtail Gene / Short Tail)
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Breeds
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Australian Shepherd
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Australian Stumpy tail cattle Dog
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Austrian Pinscher
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Bourbonnais Pointer
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Bouvier des Ardennes
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Brazilian Terrier
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Brittany Spaniel
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Croatian Sheepdog
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Danish Farm Dog
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Jack Russell Terrier
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Karelian Bear Dog
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Mudi
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Polish Lowland sheepdog
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Pyrenean Shepherd
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Savoy Sheepdog
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Schipperke
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Spanish Water Dog
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Spanish Waterdog
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Swedish Farm Dog
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Swedish Vallhund
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Welsh Corgi
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Description |
this test enables you to identify if a dog is docked or has a natural short tail. This conditioned is caused by the Brachyury mutation, the trait of inheritance is autosomal dominant which means that dogs who carry one or two copies of the mutation will have a natural short tail. Dogs with two copies of the normal gene will have normal tail.
Possible results:
Normal: The dog have two copies of the normal gene and will have a normal tail.
Heterozygous: The dog carries one copy of the normal gene and one copy of the mutant gene, the dog has a natural short tail. Heterozygous dogs can pass the mutation to their offspring with a probbility of 50%.
Homozygous for the mutation: the dog carries two copy of the mutant gene and has a natural short tail. The dog will pass the mutation to its entire offspring who will all have natural short tail. In six breed additional studied there is no correlation between the analysed mutation and a short tail: Boston Terrier, English Bulldog, King Charles Spaniel, Miniature Schnauzer, Parson Russell Terrier, Rottweiler
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Sample Requirements |
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal swabs. .
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2 ) Degenerative Myelopathy / Degenerative Radiculomyelopathy) DM (Exon 2)
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Breeds
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Airedale Terrier
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Alaskan Malamute
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All Dog Breeds
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American Eskimo
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Bernese Mountain Dog
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Bloodhound
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Borzoi (Russian Wolfhound)
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Boxer
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British Timber Dog
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Cavalier King Charles Spaniel
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Canaan Dog
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Cardigan Welsh Corgi
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Chesapeake Bay Retriever
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Fox Terrier
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French Bull Dog
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German Shepherd
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Glen Of Imaal Terrier
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Golden Retriever
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Pyrenean Mountain Dog (Great Pyrenees)
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Hovawart
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Pumi ( Hungarian Pumi / Pumik )
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Jack Russell Terrier
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Kerry Blue Terrier
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Labrador Retriever
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Lakeland Terrier
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Northern Inuit
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Nova Scotia Duck tolling Retriever ( NSDTR )
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Pembroke Welsh Corgi
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Poodle
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Pug
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Rhodesian Ridgeback
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Rough Collie
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Soft Coated Wheaten Terrier
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Shetland Sheepdog (Sheltie)
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Smooth Collie
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Utonagan
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Wire Fox Terrier
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Kennel Club
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This test is part of the Official UK Kennel Club DNA Testing Scheme in Chesapeake Bay Retriever , French Bull Dog , German Shepherd , Nova Scotia Duck tolling Retriever ( NSDTR ) , Rough Collie , and Smooth Collie.
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The Disease |
Canine degenerative myelopathy (also known as chronic degenerative radiculomyelopathy) is a progressive disease of the spinal cord in older dogs. The disease has an insidious onset typically between 7 and 14 years of age. It begins with a loss of coordination (ataxia) in the hind limbs. As of July 15, 2008 the mutated gene responsible for DM has been found present in 43 breeds including German Shepherds, Boxers, Chesapeake Bay Retrievers, Rhodesian Ridgebacks, and both breeds of Welsh Corgis. The disease is chronic and progressive, and resulting in paralysis.
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Clinical Signs |
Degenerative myelopathy initially affects the back legs and causes muscle weakness and loss, and lack of coordination. These cause a staggering effect that may appear to be arthritis. The dog may drag one or both rear paws when it walks. This dragging can cause the nails of one foot to be worn down. The condition may lead to extensive paralysis of the back legs. As the disease progresses, the animal may display symptoms such as incontinence and has considerable difficulties with both balance and walking. If allowed to progress, the animal will show front limb involvement and extensive muscle atrophy. Eventually cranial nerve or respiratory muscle involvement necessitates euthanasia.
Progression of the disease is generally slow but highly variable. The animal could be crippled within a few months, or may survive up to three years
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Trait of Inheritance |
Tow alleles are invloved in Degenerative Myelopathy, A and G, therefore a test result can be A/A, A/G, or G/G.
Mode of inheritance is autosomal recessive with variable penetrance;
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Inheritance : AUTOSOMAL
RECESSIVE
trait
Sire
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Dam
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Offspring
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clear
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clear
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100% clear
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clear
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carrier
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50% clear + 50%
carriers
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clear
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affected
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100% carriers
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carrier
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clear
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50% clear + 50%
carriers
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carrier
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carrier
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25% clear + 25% affected
+ 50% carriers
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carrier
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affected
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50% carriers + 50%
affected
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affected
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clear
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100% carriers
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affected
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carrier
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50% carriers + 50%
affected
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affected
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affected
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100% affected
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Clear
Genotype: N / N [ Homozygous normal ]
The dog is noncarrier of the mutant gene.
It is very unlikely that the dog will show signs of the Degenerative Myelopathy
Carrier
Genotype: N / DM (Exon 2) [ Heterozygous ]
The dog carries one copy of the mutant gene and one
copy of the normal gene.
It is very unlikely that the dog will show signs of the Degenerative Myelopathy
Affected
Genotype: DM (Exon 2) / DM (Exon 2) [ Homozygous mutant ]
The dog carries two copies of the mutant gene and
therefore it will pass the mutant gene to its entire offspring.
The dog may or may not show signs of the disease
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Sample Requirements |
Buccal Swabs or 0.5 - 1 ml blood in EDTA Blood Tube
Buccal swabs or 0.5 - 1 ml blood in EDTA Blood Tube .
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3 ) Neuroaxonal Dystrophy ( NAD )
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Breeds
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Papillon
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Rottweiler
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Spanish Water Dog
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Kennel Club
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This test is part of the Official UK Kennel Club DNA Testing Scheme in Papillon , and Spanish Water Dog.
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The Disease |
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Neuroaxonal Dystrophy in Spanish Water Dogs is an uncharacterized juvenile-onset genetic disorder that affect Spanish Water Dogs. Affected dogs exhibits various neurological deficits including gait abnormalities and behavioral deficits.
Symptoms include slowly progressing neurological signs starting between six and eleven months of age. Owners of affected dogs reported gait abnormalities, behavioral changes (dullness, nervousness, vocalization) and incontinence alone or in combination with uncontrolled defecation. Mild head tilt, generalized mild cerebellar ataxia with hypermetria of the thoracic limbs and absent to depressed patellar reflexed. Additionally, affected dogs displayed varying degrees of compulsory pacing, proprioceptive deficits, decreased menace, visual deficits, positional nystagmus and decreased muscle tone.
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Trait of Inheritance |
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Inheritance : AUTOSOMAL
RECESSIVE
trait
Sire
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Dam
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Offspring
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clear
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clear
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100% clear
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clear
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carrier
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50% clear + 50%
carriers
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clear
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affected
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100% carriers
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carrier
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clear
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50% clear + 50%
carriers
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carrier
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carrier
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25% clear + 25% affected
+ 50% carriers
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carrier
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affected
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50% carriers + 50%
affected
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affected
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clear
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100% carriers
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affected
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carrier
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50% carriers + 50%
affected
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affected
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affected
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100% affected
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Clear
Genotype: N / N [ Homozygous normal ]
The dog is noncarrier of the mutant gene.
It is very unlikely that the dog will develop Neuroaxonal Dystrophy ( NAD ). The dog will never pass the mutation to its offspring, and therefore it can be bred to any other dog.
Carrier
Genotype: N / NAD [ Heterozygous ]
The dog carries one copy of the mutant gene and one
copy of the normal gene.
It is very unlikely that the dog will develop Neuroaxonal Dystrophy ( NAD ) but since it carries the mutant gene, it can pass it on to its offspring with the probability of 50%. Carriers should only be bred to clear dogs. Avoid breeding carrier to carrier because 25% of their offspring is expected to be affected (see table above)
Affected
Genotype: NAD / NAD [ Homozygous mutant ]
The dog carries two copies of the mutant gene and
therefore it will pass the mutant gene to its entire offspring.
The dog is likely to develop Neuroaxonal Dystrophy ( NAD ) and will pass the mutant gene to its entire offspring
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Description |
In Spanish Water dog the disease is caused by a mutation in the TECPR2 gene. In Papillon, the disease is caused by a mutation in the PLA2G6 gene.
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Sample Requirements |
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal swabs. .
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4 ) Progressive Retinal Atrophy (prcd-PRA) Option 1: (8094P / 8127)
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Kennel Club: results of this test is accepted by the Kennel Club
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Breeds
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American Cocker Spaniel
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American Eskimo
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Australian cattle dog
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Australian Shepherd
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Australian Stumpy Tail Cattle Dog
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Australian Stumpy tail cattle Dog
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Barbet (French Water Dog)
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Bearded Collie
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Bolognese
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Bolonka Zwetna
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Chesapeake Bay Retriever
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Chihuahua
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Chinese Crested
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Cockapoo (English)
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Cockapoo (American)
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Cocker Spaniel
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Dwarf poodle
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English Cocker Spaniel
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English shepherd
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Entlebuch Mountain dog
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Finnish Lapphund
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German Spitz
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Giant Schnauzer
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Golden Retriever
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Jack Russell Terrier
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Karelian Bear Dog
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Kuvasz
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Labradoodle
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Labrador Retriever
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Lagotto Romagnolo
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Lapponian Herder
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Markiesje
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Miniature Poodle
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Miniature American Shepherd
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Norwegian Elkhound
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Nova Scotia Duck tolling Retriever ( NSDTR )
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Parson Russell Terrier (PRT)
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Poodle
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Portuguese Waterdog
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Schipperke
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Australian Silky Terrier
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Spanish Water Dog
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Standard Poodle
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Swedish Lapp Hund
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Toy Poodle
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Waeller (Wäller)
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Yorkshire Terrier
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Kennel Club
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This test is part of the Official UK Kennel Club DNA Testing Scheme in Australian cattle dog , Australian Shepherd , Chesapeake Bay Retriever , Chinese Crested , Cocker Spaniel , English Cocker Spaniel , Entlebuch Mountain dog , Finnish Lapphund , Giant Schnauzer , Labrador Retriever , Miniature Poodle , Norwegian Elkhound , Nova Scotia Duck tolling Retriever ( NSDTR ) , Portuguese Waterdog , Spanish Water Dog , Standard Poodle , and Toy Poodle.
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The Disease |
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Progressive retinal atrophy (PRA) as an inherited disease occurs in many dog breeds and also in different forms. The form of progressive rod-cone degeneration (prcd-PRA) is a photoreceptor degeneration in dogs with varying ages of onset. This genetic disorder causes the degeneration of retinal cells in the eye: firstly, rod cells are affected, thus leading to progressive night blindness. Secondly, degeneration of the cone cells results in complete blindness of the dog, even in full light situations during the day.
Age of onset of clinical symptoms is typically in early adolescence or early adulthood. However, the onset of the disease may vary among different dog breeds.
Since diagnosis of retinal diseases in dogs may prove difficult, the genetic test on prcd-PRA helps to diagnose a specific disease and is also a useful tool for breeders to eliminate the mutated gene from the dog population.
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Trait of Inheritance |
The mutation in the PRCD gene which has been suggested to cause prcd-PRA has recently been published by the group of Gustavo D. Aguirre at the University of Pennsylvania, USA, and could be found in several dog breeds.
Prcd-PRA is inherited as an autosomal recessive trait. So there are three conditions a dog can be: it can be clear (genotype N/N or homozygous normal) meaning that it does not carry the mutation and will not develop the prcd-form of PRA. Since it also cannot pass the mutation onto its offspring, it can be mated to any other dog.
A dog which has one copy of the PRCD gene with the mutation and one copy without the mutation is called a carrier or heterozygous (genotype N/PRA); while it will not be affected by prcd-PRA, it can pass the mutation onto its offspring and should therefore only be mated to clear dogs.
Dogs that develop this form of PRA have two PRCD gene copies with the mutation (genotype PRA/PRA or homozygous affected); they will always pass the mutated gene onto their offspring and should also be mated only to clear dogs..
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Inheritance : AUTOSOMAL
RECESSIVE
trait
Sire
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Dam
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Offspring
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clear
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clear
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100% clear
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clear
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carrier
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50% clear + 50%
carriers
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clear
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affected
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100% carriers
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carrier
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clear
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50% clear + 50%
carriers
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carrier
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carrier
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25% clear + 25% affected
+ 50% carriers
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carrier
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affected
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50% carriers + 50%
affected
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affected
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clear
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100% carriers
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affected
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carrier
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50% carriers + 50%
affected
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affected
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affected
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100% affected
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Clear
Genotype: N / N [ Homozygous normal ]
The dog is noncarrier of the mutant gene.
It is very unlikely that the dog will develop Progressive Retinal Atrophy (prcd-PRA) Option 1: (8094P / 8127). The dog will never pass the mutation to its offspring, and therefore it can be bred to any other dog.
Carrier
Genotype: N / PRA [ Heterozygous ]
The dog carries one copy of the mutant gene and one
copy of the normal gene.
It is very unlikely that the dog will develop Progressive Retinal Atrophy (prcd-PRA) Option 1: (8094P / 8127) but since it carries the mutant gene, it can pass it on to its offspring with the probability of 50%. Carriers should only be bred to clear dogs. Avoid breeding carrier to carrier because 25% of their offspring is expected to be affected (see table above)
Affected
Genotype: PRA / PRA [ Homozygous mutant ]
The dog carries two copies of the mutant gene and
therefore it will pass the mutant gene to its entire offspring.
The dog is likely to develop Progressive Retinal Atrophy (prcd-PRA) Option 1: (8094P / 8127) and will pass the mutant gene to its entire offspring
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Sample Requirements |
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal swabs. .
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5 ) Congenital Hypothyreosis / hypothyroidism ( CHG )
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Breeds
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Fox Terrier
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French Bull Dog
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Rat Terrier
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Spanish Water Dog
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Tenterfield Terrier
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Kennel Club
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This test is part of the Official UK Kennel Club DNA Testing Scheme in Spanish Water Dog.
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The Disease |
Hypothyreosis stands for all different kind of thyroid gland sub-function, independent of the origin. A lot of symptoms relate to Hypothyreosis including general symptoms like lethargy or increase in weight, as well as problems concerning heart, skin and nerves. In Spanish Water Dogs sub-function of the thyroid gland can originate from a genetic source.
Affected dogs have a very short lifespan and normally die as puppies.
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Trait of Inheritance |
Autosomal recessive
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Inheritance : AUTOSOMAL
RECESSIVE
trait
Sire
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Dam
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Offspring
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clear
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clear
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100% clear
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clear
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carrier
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50% clear + 50%
carriers
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clear
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affected
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100% carriers
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carrier
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clear
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50% clear + 50%
carriers
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carrier
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carrier
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25% clear + 25% affected
+ 50% carriers
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carrier
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affected
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50% carriers + 50%
affected
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affected
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clear
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100% carriers
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affected
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carrier
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50% carriers + 50%
affected
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affected
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affected
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100% affected
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Clear
Genotype: N / N [ Homozygous normal ]
The dog is noncarrier of the mutant gene.
It is very unlikely that the dog will develop Congenital Hypothyreosis / hypothyroidism ( CHG ). The dog will never pass the mutation to its offspring, and therefore it can be bred to any other dog.
Carrier
Genotype: N / CHG [ Heterozygous ]
The dog carries one copy of the mutant gene and one
copy of the normal gene.
It is very unlikely that the dog will develop Congenital Hypothyreosis / hypothyroidism ( CHG ) but since it carries the mutant gene, it can pass it on to its offspring with the probability of 50%. Carriers should only be bred to clear dogs. Avoid breeding carrier to carrier because 25% of their offspring is expected to be affected (see table above)
Affected
Genotype: CHG / CHG [ Homozygous mutant ]
The dog carries two copies of the mutant gene and
therefore it will pass the mutant gene to its entire offspring.
The dog is likely to develop Congenital Hypothyreosis / hypothyroidism ( CHG ) and will pass the mutant gene to its entire offspring
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Sample Requirements |
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal swabs. .
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Price
for the above 5 tests
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£ 156.00 (including VAT)
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To order:
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Download
Order Form from this link 
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Complete the order form and send it together
with your samples to the following address:
Laboklin (UK), 125 Northenden Road, Manchester, M33 3HF
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See Also: |
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Copper Toxicosis (Copper Storage Disease )
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Progressive Retinal Atrophy (Dominant PRA)
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Globoid Cell Leukodystrophy (Krabbe Disease)
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CSNB (Congenital Stationary Night Blindness)
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CLAD (Canine Leukocyte Adhesion Deficiency)
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Cystinuria
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von Willebrand disease Type II (vWD II)
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PK Deficiency (Pyruvate Kinase Deficiency)
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Fucosidosis
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PFK Deficiency (Phosphofructokinase deficiency)
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Myotonia Congenita
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MH (Malignant Hyperthermia)
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X-Linked Severe Combined Immunodeficiency (X-SCID)
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GM1-Gangliosidosis
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Narcolepsy
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Muscular Dystrophy (MD)
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MPS ( Mucopolysaccharidosis type VII)
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Hereditary Myopathy / Centronuclear Myopathy (HMLR, CNM)
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Canine Cyclic Neutropenia (Gray Collie Syndrome)
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Progressive Retinal Atrophy (cord1- PRA / crd4 PRA)
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L-2-HGA ( L- 2 - hydroxyglutaric aciduria )
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von Willebrand disease Type I (vWD I)
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von Willebrand disease Type III (vWD III)
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Neuronal Ceroid Lipofuscinosis ( CL / NCL )
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Trapped Neutrophil Syndrome ( TNS )
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Progressive Retinal Atrophy (crd PRA)
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PDP 1 Deficiency (Pyruvate Dehydrogenase Phosphatase 1 Deficiency)
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Factor VII Deficiency
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Progressive Retinal Atrophy (rcd1 PRA)
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Progressive Retinal Atrophy (rcd1a PRA)
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Juvenile Brain Disease ( JBD ) / Juvenile Encephalopathy ( Epilepsy )
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Microphthalmia ( RBP4 )
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French Bulldog DNA bundle
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Leonberger DNA bundle
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Lethal Acrodematitis ( LAD )
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BRAF Mutation ( transitional cell carcinoma )
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MDR1 Gene Varian / Ivermectin Sensitivity *
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Exercise Induced Collapse ( EIC )
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Dwarfism (Pituitary Dwarfism / Hypopituitarism)
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Degenerative Myelopathy / Degenerative Radiculomyelopathy) DM (Exon 2)
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Greyhound Neuropathy (Hereditary Neuropathy)
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Brittle Bone Disease (Osteogenesis Imperfecta)
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Glycogen Storage Disease (GSDllla)
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Hereditary Cataract (HSF4)
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Neonatal encephalopathy (NE / NEWS)
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Haemophilia B (factor IX deficiency)
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JEB (Junctional Epidermolysis bullosa)
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Primary Lens Luxation (PLL)
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Brachyury (Bobtail Gene / Short Tail)
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Familial Nephropathy (FN) / Hereditary Nephropathy *
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Startle Disease (SD) / Hyperekplexia
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Familial Nephropathy (FN) / Hereditary Nephropathy
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Myostatin Mutation ("Bully" Whippet)/ Double Muscling
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Hereditary Nephritis / Samoyed Hereditary Glomerulopathy
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Episodic Falling in Cavalier King Charles Spaniel (EF)
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Dry Eye and Curly Coat syndrome (CCS)
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CKCS Pack A: Episodic Falling + Dry Eye Curly Coat syndrome
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Haemophilia A (factor VIII deficiency)
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Congenital Hypothyreosis / hypothyroidism ( CHG )
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Hereditary Nasal Parakeratosis (HNPK)
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Juvenile Epilepsy (JE)
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Musladin-Lueke syndrome (MLS)
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Ichthyosis *
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Neonatal Cortical Cerebellar Abiotrophy (NCCD)
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Dwarfism (Skeletal Dysplasia 2 / SD2 )
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Primary Open Angle Glaucoma (POAG)
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Progressive Retinal Atrophy (generalized PRA)
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Progressive Retinal Atrophy (GR-PRA1)
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Progressive retinal atrophy ( rcd4-PRA) / LOPRA
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Alaskan Malamute Polyneuropathy (AMPN / IPAM / HPAM)
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Pug Dog Encephalitis (PDE) / Necrotizing Meningoencephalitis (NME)
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Polycystic Kidney Disease (PKD)
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Pompe's Disease (Glycogen Storage Disease type II / GSDII)
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Primary ciliary dyskinesia (PCD)
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Protein Losing Nephropathy (PLN)
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Late Onset Ataxia (LOA)
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Cobalamin Malabsorption (Imerslund-Gräsbeck syndrome (IGS))
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Collie Eye Anomaly (CEA) / Choroidal Hypoplasia (CH) Option 2 Optigen*
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Retinal Dysplasia (RD) / Oculo Skeletal Dysplasia (OSD)*
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Spinocerebellar ataxia (SCA)
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Cystinuria (Dominant)
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pap-PRA1 (Progressive Retinal Atrophy)
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Progressive Retinal Atrophy (BAS PRA)
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CMSD (Canine Multiple System Degeneration)
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Hereditary Cataract (HSF4) *
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Special offer 4: Juvenile Epilepsy + Furnishing + LSD
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Progressive Retinal Atrophy (prcd-PRA) Option 2: Optigen (8094X)
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Progressive Retinal Atrophy (prcd-PRA) Option 1: (8094P / 8127)
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Thrombopathia (Thrombopathy)
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Digital Hyperkeratosis (DH) (Hereditary Footpad Hyperkeratosis / Corny Feet)
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Degenerative Myelopathy / degenerative radiculomyelopathy) DM (Exon 1)
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Degenerative Myelopathy / degenerative radiculomyelopathy) DM (Exon 1 + Exon 2)
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Ectodermal Dysplasia / Skin Fragility Syndrome (ED / SFS)
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Hypomyelination (Shaking Puppy Syndrome) SPS
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Type A PRA * Optigen)
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JRT and PRT Pack A: Late Onset Ataxia (LOA) + Spinocerebellar Attaxia (SCA)
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JRT and PRT Pack B:Late Onset Ataxia (LOA) + Spinocerebellar Attaxia (SCA) + PLL + JBD
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Leonberger Polyneuropathy 1 ( LPN1)
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Hereditary Ataxia (HA)
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Finnish Hound Ataxia / Cerebellar Ataxia (FHA / CAFH)
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Dandy-Walker-Like Malformation (DWLM)
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Persistent Müllerian duct syndrome (PMDS)
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Cone Degeneration (CD) by OptiGen *
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Fanconi Syndrome (FS)
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Lagotto Storage Disease (LSD)
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Juvenile Laryngeal Paralysis & Polyneuropathy (JLPP)
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Progressive Retinal Atrophy (CNGA1 PRA)
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Achromatopsia (day blindness) / ACHM
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Progressive Retinal Atrophy (GR-PRA2)
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Unspecified test
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Postoperative Hemorrhage (P2Y12 / P2RY12)
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Glanzmann Thrombasthenia (Thrombasthenia, Thrombasthenic thrombopathia, GT)
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Prekallikrein Deficiency (KTK) / Fletcher Factor Deficiency
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C3 Deficiency (Complement Component 3 deficiency)
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Congenital Myasthenic Syndrome (CMS)
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Bardet Biedl Syndrome (BBS)
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GM2 Gangliosidosis Variant 0 (Sandhoff Disease)
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Macrothrombocytopenia ( MTC-D )
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Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
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Vitamin D-dependent Rickets (HVDRR)
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Amelogenesis Imperfecta (AI) / Familial Enamel Hypoplasia (FEH)
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X-linked Myotubular Myopathy (XLMTM)
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Collie Eye Anomaly (CEA) / Choroidal Hypoplasia (CH) Option 1*
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Macrothrombocytopenia ( MTC- R )
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Muscular Dystrophy (MDL)
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Mucopolysaccharidosis type IIIa (MPS IIIA)
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Neuroaxonal Dystrophy ( NAD )
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Progressive Retinal Atrophy (rcd2-PRA) Option 1 by Laboklin
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Ichthyosis ( Epidermolytic Hyperkeratosis (EHK) )
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May-Hegglin Anomaly (MHA)
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Alaskan Husky Encephalopathy (AHE)
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Cerebral Dysfunction (CDF)
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Dwarfism ( Chondrodysplasia )
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Ichthyosis (Congenital Ichthyosis / Great Dane Ichthyosis)
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Hemorrhagic Diathesis / Bleeding Diathesis (Canine Scott Syndrom)
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Glycogen storage disease type Ia (GSD Ia) / VON Grieke Disease
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Gallbladder Mucoceles
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Primary Hyperoxaluria type I (PH I)
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Hyperuricosuria / Urate Stones (HUU, SLC)
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Severe Combined Immunodeficiency (SCID)
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Leukocyte Adhesion Deficiency type III (LAD III)
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Cleft Lip / Palate and Syndactyly (CLPS)
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Progressive Retinal Atrophy (crd1 PRA)
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Progressive Retinal Atrophy (CRD2 PRA)
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Spondylocostal Dysostosis (Comma Defect)
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Canine Multi-Focal Retinopathy (CMR)
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Craniomandibular Osteopathy (CMO)
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Retinal Dysplasia (RD) / Oculo Skeletal Dysplasia (OSD)*
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Special Offer: DM (Exon 2) + MDR1
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Special Offer Chinese Crested: PLL + prcd PRA Option 1 + rcd3 PRA + DM Exon 2
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Warbung Micro Syndrome 1 (WARBM1)
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Raine Syndrome
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van den Ende-Gupta Syndrom (VDEGS)
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Lundehund-Syndrome ( Lymphagetasia )
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Obesity / Adiposity ( ADI )
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Alexander Disease (AxD) / Leukodystrophy
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Spinal Dysraphism / Neural Tube Defects ( NTD )
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Spongy Degeneration with Cerebellar Ataxia ( SDCA1 )
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XL - PRA (Progressive retinal Atrophy)
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Nemaline Myopathy (NM)
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Beagle DNA Bundle : IGS + Factor VII + MLS + NCCD + Osteogenesis imperfecta + PK + POAG
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Poodle DNA Bundle: DM exon2 + rcd4 PRA + NE + prcd-PRA option 1 + vWD1
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Golden Retriever DNA bundle: GR-PRA1 + GR-PRA2 + Ichthyosis + prcd-PRA option 1 + Muscular Dystrophy (MD)
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Pug Special Offer: DM Exon2 + MH + PDE / NME + PK + PLL
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Aussie DNA bundle: CEA option * + DM exon2 + HSF4 + MDR1 + MH + NCL + prcd-PRA Option 1*
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Collie DNA Bundle: CEA Option 1 + DM exon2 + HUU (SLC) + MDR1 + rcd2-PRA
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Border Collie DNA Bundle: CEA Option 1 + IGS + MDR1 + Raine + SN + NCL + TNS + GGD
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Pack A: CNM + DM exon2 + EIC + HNPK + OSD option 1 + prcd-PRA option 1 + SD2
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Pack B: AxD + Cystinuria + Narcolepsy + Obesity + PK + SLC + XL-MTM
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Ichthyosis
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Catalase Deficiency ( CAT ) / Hypocatalasemia / Acatalasia
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Juvenile Myoclonic Epilepsy ( JME )
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Paroxysmal Dyskinesia ( PxD )
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Spongy Degeneration with Cerebellar Ataxia ( SDCA2 )
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Belgian Shepherd Special Offer : SDCA1 + SDCA2
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Sensory Neuropathy ( SN )
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Acute Respiratory Distress Syndrome ( ARDS )
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POAG / PLL Primary Open Angle Glaucoma (POAG) and Primary Lens Luxation (PLL)
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Shar Pei auto-inflammatory disease (SPAID)
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Dystrophic Epidermolysis Bullosa (DEB)
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Doberman DNA bundle (DM2 + vWDI + Narcolepsy + B Locus + D Locus)
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Landseer DNA bundle (Cystinuria + DM2 + SLC + MD + Thrombopathia)
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Rhodesian Ridgeback DNA Bundle (DM2 + Haemophilia B + B Locus + JME + D Locus)
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Rottweiler DNA bundle ( DM2 , SLC , JLPP , CL1 , XL - MTM )
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Leonberger Polyneuropathy 2 ( LPN2 )
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Hereditary Nasal Parakeratosis (HNPK)
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Subacute Necrotizing Encephalopathy (SNE)
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ISDS Exclusive Border Collie DNA Bundle: CEA 1* + IGS + SN + TNS
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Acral Mutilation Syndrome ( AMS )
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Lafora Disease (LAF / LD) / Myoclonic Epilepsy
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Shetland DNA Bundle: CEA option 1 + DM Exon 2 + vWD Type III + MDR1 + CNGA1-PRA
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CKCS Pack B: DM Exon2 + Episodic Falling + DryEye + MD + MTC
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Progressive Retinal Atrophy (rcd3 PRA)
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Old English Sheepdog (Bobtail) DNA bundle: DM Exon2 + EIC + HA + MDR1 + PCD
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German Shepherd and Wolfdog DNA Bundle
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Glaucoma and Goniodysgenesis (GGD)
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Leukoencephalomyelopathy ( LEMP )
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Hereditary Deafness ( PTPRQ )
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Type B PRA * (Optigen)
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Neuronal Ceroid Lipofuscinosis Combi in ACD & AUSSIE ( NCL Combi )
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Chondrodystrophy (CDDY with IVDD Risk) and Chondrodysplasia (CDPA)
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Mycobacterium Avium Complex ( MAC ) sensitivity
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Australian Cattle Dog bundle (DM Exon2 + NCL + PLL + prcd-PRA (partnerlab) + rcd4-PRA)
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Dachshund DNA bundle (IVDD-risk + Osteogenesis imperfecta + NCL + cord1-PRA + crd-PRA)
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English Springer Spaniel DNA bundle (AMS + FN + SPS + Fucosidosis + PFKD + cord1-PRA )
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Welsh Corgi DNA bundle (Brachyuria + IVDD-risk + DM exon2 + rcd3-PRA + vWD1)
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Cocker Spaniel DNA bundle (AMS + FN + prcd PRA option 1)
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Leukoencephalopathy ( LEP )
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Larynx / Laryngeal Paralysis ( LP )
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 |
Dilated Cardiomyopathy ( DCM )
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Mucopolysaccharidosis type IIIb ( MPS3b )
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Renal dysplasia and hepatic fibrosis ( RDHN )
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Stargardt disease ( STGD )
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NECAP-1 Progressive Retinal Atrophy ( NECAP1 PRA / NECAP PRA5)
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SCWT DNA bundle (DM + PLN + PxD + RBP4 + SLC )
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Inflammatory Pulmonary Disease ( IPD )
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Hypophosphatasia ( HPP )
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Upper Airway Syndrome ( UAS )
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Oculoskeletal Dysplasia ( OSD 3 )
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Shiba Inu DNA bundle (GM1 , GM2 , A Locus and E Locus)
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