Australian Shepherd , Australian Stumpy tail cattle Dog , Austrian Pinscher , Bourbonnais Pointer , Bouvier des Ardennes , Brazilian Terrier , Brittany Spaniel , Croatian Sheepdog , Danish Farm Dog , Jack Russell Terrier , Karelian Bear Dog , Mudi , Polish Lowland sheepdog , Pyrenean Shepherd , Savoy Sheepdog , Schipperke , Spanish Water Dog , Spanish Waterdog , Swedish Farm Dog , Swedish Vallhund , Welsh Corgi .

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal swabs. .

2 - 3 weeks

Airedale Terrier , Alaskan Malamute , All Dog Breeds , American Eskimo , Bernese Mountain Dog , Bloodhound , Borzoi (Russian Wolfhound) , Boxer , British Timber Dog , Cavalier King Charles Spaniel , Canaan Dog , Cardigan Welsh Corgi , Chesapeake Bay Retriever , Fox Terrier , French Bull Dog , German Shepherd , Glen Of Imaal Terrier ( GIT ) , Golden Retriever , Pyrenean Mountain Dog (Great Pyrenees) , Hovawart , Pumi ( Hungarian Pumi / Pumik ) , Jack Russell Terrier , Kerry Blue Terrier , Labrador Retriever , Lakeland Terrier , Northern Inuit , Nova Scotia Duck tolling Retriever ( NSDTR ) , Pembroke Welsh Corgi , Poodle , Pug , Rhodesian Ridgeback , Rough Collie , Soft Coated Wheaten Terrier , Shetland Sheepdog (Sheltie) , Smooth Collie , Utonagan , Wire Fox Terrier .

This test is part of the Official UK Kennel Club DNA Testing Scheme in Chesapeake Bay Retriever , French Bull Dog , German Shepherd , Nova Scotia Duck tolling Retriever ( NSDTR ) , Rough Collie , and Smooth Collie.

Degenerative myelopathy initially affects the back legs and causes muscle weakness and loss, and lack of coordination. These cause a staggering effect that may appear to be arthritis. The dog may drag one or both rear paws when it walks. This dragging can cause the nails of one foot to be worn down. The condition may lead to extensive paralysis of the back legs. As the disease progresses, the animal may display symptoms such as incontinence and has considerable difficulties with both balance and walking. If allowed to progress, the animal will show front limb involvement and extensive muscle atrophy. Eventually cranial nerve or respiratory muscle involvement necessitates euthanasia. Progression of the disease is generally slow but highly variable. The animal could be crippled within a few months, or may survive up to three years

Tow alleles are invloved in Degenerative Myelopathy, A and G, therefore a test result can be A/A, A/G, or G/G.

Mode of inheritance is autosomal recessive with variable penetrance;

Sire		Dam		Offspring
clear		clear		100% clear
clear		carrier		50%  clear + 50% carriers
clear		affected		100% carriers
carrier		clear		50%  clear + 50% carriers
carrier		carrier		25% clear + 25% affected + 50% carriers
carrier		affected		50% carriers + 50% affected
affected		clear		100%  carriers
affected		carrier		50% carriers + 50% affected
affected		affected		100% affected

Buccal Swabs or 0.5 - 1 ml blood in EDTA Blood Tube

Buccal swabs or 0.5 - 1 ml blood in EDTA Blood Tube .

1 - 2 weeks

Lagotto Romagnolo , Papillon , Rottweiler , Spanish Water Dog .

This test is part of the Official UK Kennel Club DNA Testing Scheme in Papillon , and Spanish Water Dog.

.

Sire		Dam		Offspring
clear		clear		100% clear
clear		carrier		50%  clear + 50% carriers
clear		affected		100% carriers
carrier		clear		50%  clear + 50% carriers
carrier		carrier		25% clear + 25% affected + 50% carriers
carrier		affected		50% carriers + 50% affected
affected		clear		100%  carriers
affected		carrier		50% carriers + 50% affected
affected		affected		100% affected

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal swabs. .

2 - 3 weeks

American Cocker Spaniel , American Eskimo , Australian cattle dog , Australian Shepherd , Australian Stumpy Tail Cattle Dog , Australian Stumpy tail cattle Dog , Barbet (French Water Dog) , Bearded Collie , Bolognese , Bolonka Zwetna , Chesapeake Bay Retriever , Chihuahua , Chinese Crested , Cockapoo (English) , Cockapoo (American) , Cocker Spaniel , Dwarf poodle , English Cocker Spaniel , English shepherd , Entlebuch Mountain dog , Finnish Lapphund , German Spitz , Giant Schnauzer , Golden Retriever , Jack Russell Terrier , Karelian Bear Dog , Kuvasz , Labradoodle , Labrador Retriever , Lagotto Romagnolo , Lapponian Herder , Markiesje , Miniature Poodle , Miniature American Shepherd , Norwegian Elkhound , Nova Scotia Duck tolling Retriever ( NSDTR ) , Parson Russell Terrier (PRT) , Poodle , Portuguese Waterdog , Schipperke , Australian Silky Terrier , Spanish Water Dog , Standard Poodle , Swedish Lapp Hund , Toy Poodle , Waeller (Wäller) , Yorkshire Terrier .

This test is part of the Official UK Kennel Club DNA Testing Scheme in Australian cattle dog , Australian Shepherd , Chesapeake Bay Retriever , Chinese Crested , Cocker Spaniel , English Cocker Spaniel , Entlebuch Mountain dog , Finnish Lapphund , Giant Schnauzer , Labrador Retriever , Miniature Poodle , Norwegian Elkhound , Nova Scotia Duck tolling Retriever ( NSDTR ) , Portuguese Waterdog , Spanish Water Dog , Standard Poodle , and Toy Poodle.

The mutation in the PRCD gene which has been suggested to cause prcd-PRA has recently been published by the group of Gustavo D. Aguirre at the University of Pennsylvania, USA, and could be found in several dog breeds. Prcd-PRA is inherited as an autosomal recessive trait. So there are three conditions a dog can be: it can be clear (genotype N/N or homozygous normal) meaning that it does not carry the mutation and will not develop the prcd-form of PRA. Since it also cannot pass the mutation onto its offspring, it can be mated to any other dog.

A dog which has one copy of the PRCD gene with the mutation and one copy without the mutation is called a carrier or heterozygous (genotype N/PRA); while it will not be affected by prcd-PRA, it can pass the mutation onto its offspring and should therefore only be mated to clear dogs. Dogs that develop this form of PRA have two PRCD gene copies with the mutation (genotype PRA/PRA or homozygous affected); they will always pass the mutated gene onto their offspring and should also be mated only to clear dogs..

Sire		Dam		Offspring
clear		clear		100% clear
clear		carrier		50%  clear + 50% carriers
clear		affected		100% carriers
carrier		clear		50%  clear + 50% carriers
carrier		carrier		25% clear + 25% affected + 50% carriers
carrier		affected		50% carriers + 50% affected
affected		clear		100%  carriers
affected		carrier		50% carriers + 50% affected
affected		affected		100% affected

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal swabs. .

2 - 3 weeks

Fox Terrier , French Bull Dog , Rat Terrier , Spanish Water Dog , Tenterfield Terrier .

This test is part of the Official UK Kennel Club DNA Testing Scheme in Spanish Water Dog.

Autosomal recessive

Sire		Dam		Offspring
clear		clear		100% clear
clear		carrier		50%  clear + 50% carriers
clear		affected		100% carriers
carrier		clear		50%  clear + 50% carriers
carrier		carrier		25% clear + 25% affected + 50% carriers
carrier		affected		50% carriers + 50% affected
affected		clear		100%  carriers
affected		carrier		50% carriers + 50% affected
affected		affected		100% affected

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.

Whole blood in EDTA tube (0.5 - 1 ml) or Buccal swabs. .

2 - 3 weeks

£ 156.00 (including VAT)