Genotype: N / N [ Homozygous normal ]
The dog is noncarrier of the mutant gene.
It is very unlikely that the dog will develop Startle Disease (SD) / Hyperekplexia. The dog will never pass the mutation to its offspring, and therefore it can be bred to any other dog.
Genotype: N / SD [ Heterozygous ]
The dog carries one copy of the mutant gene and one
copy of the normal gene.
The dog carries one copy of the mutated form of the gene. Because of the recessive mode of inheritance, it is unlikely that the dog will suffer from Startle Disease, however there is a 50% chance that the dog will pass on the mutation to its offspring.
Genotype: SD / SD [ Homozygous mutant ]
The dog carries two copies of the mutant gene and
therefore it will pass the mutant gene to its entire offspring.
Homozygous affected dogs have a high risk to suffer from Startle Disease. The dog will pass on the mutation to a 100% of her offspring.