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Feline Special Offer:
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HCM, HCR, GSD4, PKD, PRA, PK-Def., SMA, Blood Groups

new test: Craniomandibular Osteopathy (CMO) in Cairn Terrier , Scottish Terrier and West Highland White Terrier
Kennel Club DNA testing schemes with LABOKLIN:
Hereditary Nasal Parakeratosis (HNPK) in Labrador Retriever
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Primary Lens Luxation (PLL) in Welsh Terrier

Hyperuricosuria / Urate Stones (HUU, SLC)

Test number: 8154D


New Kennel Club DNA testing scheme for HUU in Dalmatian
The Kennel Club has agreed a new DNA testing scheme for Hyperuricosuria (HUU) / Urate Stone Disorder (USD) in Dalmatian. Under this scheme, HUU test results can be sent by Laboklin to the Kennel Club to be recorded and published only if the submission and testing procedure complies with the following protocol:
  • that dogs to be tested are microchipped and registered before the test sample is taken;
  • that the test sample (whether buccal swab or EDTA blood sample or other) is taken by a veterinary surgeon or veterinary nurse who first confirms the microchip identity of the test subject and records both the microchip number and registration name on the sample container/package;
  • that the sample is sent directly by the veterinary surgery to LABOKLIN.

    Copies of all future test certificate results issued by LABOKLIN will only be recorded by the Kennel Club at this time provided they comply with the above protocols.

    Please ensure that the veterinary surgeon or veterinary nurse taking the sample complete the vet section on the order form, sign it and stamp it, send it directly to Laboklin and ensure that there stamp is on the package / envelope containing the samples submitted.

All Dog Breeds , Dalmatian , American Bulldog , French Bull Dog , Large Munsterlander , Bulldog , Russian Black Terrier ( RBT ) , Hungarian Vizsla .
Kennel Club
This test is part of the Official UK Kennel Club DNA Testing Scheme in Dalmatian , Large Munsterlander , Bulldog , and Russian Black Terrier ( RBT ).
The Disease
Hyperuricosuria is characterized by elevated levels of uric acid in the urine. This disease predisposes dogs to form stones in their bladders or sometimes kidneys. The trait can occur in any breed but is most commonly found in the Dalmatian, Bulldog and Black Russian Terrier.
Trait of Inheritance
Hyperuricosuria is inherited as a simple autosomal recessive trait.

Inheritance : AUTOSOMAL RECESSIVE trait







100% clear
50%  clear + 50% carriers
100% carriers
50%  clear + 50% carriers
25% clear + 25% affected + 50% carriers
50% carriers + 50% affected
100%  carriers
50% carriers + 50% affected
100% affected



Genotype: N / N [ Homozygous normal ]

The dog is noncarrier of the mutant gene.

The dog will never develop Hyperuricosuria / Urate Stones (HUU, SLC) and therefore it can be bred to any other dog.



Genotype: N / SLC2 [ Heterozygous ]

The dog carries one copy of the mutant gene and one copy of the normal gene.

The dog will never develop Hyperuricosuria / Urate Stones (HUU, SLC) but since it carries the mutant gene, it can pass it on to its offspring with the probability of 50%.

Carriers should only be bred to clear dogs.

Avoid breeding carrier to carrier because 25% of their offspring is expected to be affected (see table above)



Genotype: SLC2 / SLC2 [ Homozygous mutant ]


The dog carries two copies of the mutant gene and therefore it will pass the mutant gene to its entire offspring.

The dog will develop Hyperuricosuria / Urate Stones (HUU, SLC) and will pass the mutant gene to its entire offspring
Sample Requirements
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.
1 - 2 weeks
£ 48.00 (including VAT)

To order:

  • Download Order Form from this link pdf

  • Complete the order form and send it together with your samples to the following address:

    Laboklin (UK),   125 Northenden Road, Manchester, M33 3HF

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