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Coat Colours: D-Locus Dilution
Breeds
All Dog Breeds , Doberman Pinscher , Labrador Retriever , Newfoundland , German Pinscher , Miniature Pinscher , Rhodesian Ridgeback , Large Munsterlander .
Description

The D locus is the primary locus associated with diluted pigment, which results in coats that would otherwise be black or brown instead showing up as gray, or blue in the case of black, and pale brown or Isabella in the case of brown. The melanophilin gene has recently been shown to be responsible, but not all of the dilute causing mutations have been identified yet.

A recessive mutation in the melanophilin gene was identified as the cause of colour dilution phenotypes in the dog. Two alleles (variants) are described: the dominant full colour (D) and the recessive dilute (d). Two copies of dilute are needed to lighten black pigment to grey (often called blue) and red pigment to cream (also called buff). A diagnostic DNA test identifies the specific variants of the MLPH gene.

Sample Requirements
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs.
Turnaround
within 7 working days
Price
Number of Coat Colour Tests on the same dog Price (including VAT)
First Colour test £ 55.00
Each additional colour test on the same dog £ 28.00

To order:

  • Download Order Form from this link pdf

  • Complete the order form and send it together with your samples to the following address:

    Laboklin (UK),   125 Northenden Road, Manchester, M33 3HF

See Also:
Coat Colours: E-Locus (yellow, lemon, red, cream and appricot)  
Coat Colour: B-Locus (Brown Coat Colour)  
Coat (hair) Length  
Coat Colours: A-Locus Agouti ( fawn, sable, black and tan/tricolor, recessive black)  
Coat Colours: K- Locus  
Coat Colour: S-locus (piebald, spotted white)*  
Curly Coat *  
Furnishings and Improper Coat *  
Coat Colour EG- Locus (domino, grizzle)  
Coat Colour: EH-locus (sable)*  
Coat Colour: K-Locus and K-Locus Brindle *  
Coat Colours: EM-Locus Melanistic Mask Allele (Em), E-Locus  

 
 
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LABOKLIN GmbH & Co. KG
ISO / DIN 17025 Accredited Laboratory
© 2007 Laboklin (UK)
125 Northenden Road, Manchester, M33 3HF
Tel. 0161 282 3066