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February  2016

     
  LABOKLING @ CRUFTS 2016

 

 

We are pleased to announce that LABOKLIN will be at Crufts from 10th to 13th March 2016 and we look forward to seeing you there.

 

Our stand is located in Hall 3 opposite the restaurant, it is stand number 3-7a.

 

 

10% discount on all DNA tests submitted at Crufts !

 

  for more details please click here

 

September  2015

     
  Progressive Retinal Atrophy (Shet PRA) in Shetland Sheepdog (Sheltie)

Progressive retinal atrophy (PRA) refers to a group of genetic disease that occur in a number of dog breeds.

The disease is characterised by vision impairment caused by degeneration of the retina in both eyes leading to blindness. The mutation responsible for this disease has already been identified in a number of breeds and DNA tests have been developed to enable breeders to avoid breeding affected dogs.

PRA in shelties is clinically similar to PRA in other breeds but the mutation leading to the disease in shelties was not identified. In a recent study scientists found that in shelties there is more than one PRA variant. Scientists have been able to identify one of the mutations that causes PRA in this breed and a DNA test is now available from Laboklin. In Shelties, the disease shows a varying age on onset. In a study on affected shelties, PRA was diagnosed between the age of 2 and 11.   

  for more details please click here

 

September  2015

     
  Exercise Induced Collapse ( EIC ) has now been validated in Clumber Spaniel

We are pleased to announce the Exercise Induced Collapse DNA test has now been validated in Clumber Spaniel. We would like to thank the Clumber Spaniel Club and the Working Clumber Spaniel Society, and all Clumber Spaniel owners who submitted samples that helped in our research to validate the test in this breed.

Exercise Induced Collapse (EIC) is an inherited condition that affects a number of dog breeds including Chesapeake Bay Retriever, German Wirehaired Pointer, Labrador Retriever, Old English Sheepdog (Bobtail), Pembroke Welsh Corgi, Cocker Spaniel, Curly Coated Retriever, Boykin Spaniel and Bouvier des Flanders. EIC has now been validated in Clumber Spaniel. Affected dogs can endure mild to moderate exercise but after 5 to 20 minutes of heavy exercise with extreme excitement, the dog shows weakness and then collapse. Severely affected dogs may collapse whenever they are exercised to this extend – other dogs only exhibit collapse episodes sporadically. Signs of EIC are not typically seen until the dog begin intense training. First symptoms are usually noted between 5 months and 3 years of age. However, it is confirmed that some affected dogs did not have collapse episodes until as late as age 10.

The test is now available for ordering.  

  for more details please click here

 

August  2015

     
  Laboklin biggest ever price reductions

 

Effective from 1st September 2015

Dear Customer

Laboklin prices have not changed for the past five years, during this time, in order to cope with the ever increasing demand for our DNA testing services, we have been investing heavily in cutting edge technologies, state of the art equipment, new robotic systems and automated sample handing equipment, all operated by our highly qualified scientists. These developments did not only increase efficiency to highest attainable standards but also has now enabled us to pass on additional savings to you.

For an ISO 17025 Accredited laboratory, our prices are now exceptionally competitive.

New pricing System is effective from 1st September 2015. Until then all samples received are charged at existing prices.

CLICK HERE TO PREVIEW NEW PRICES

 

June  2015

     
  LABOKLIN will be at The UK National Dwarf German Shepherd Rally

Sunday 7th June 2015 The Elephant, Shavington, Crewe, Cheshire CW2 5DZ

We are pleased to announce that LABOKLIN will be at the UK National Dwarf German Shepherd Rally, The aim of the UK National Dwarf German Shepherd Rally is to raise awareness about Pituitary Dwarfism, an inherited condition suffered by German Shephered.

  for more details please click here

 

April  2015

     
  Adult Onset Neuropathy* (AON) in English Cocker Spaniel and Field Spaniel

 

Adult Onset Neuropathy (AON) is an inherited neurological disorder in the English Cocker Spaniel breed. Symptoms typically begins between the age of 7.5 and 9 years. The Disease is characterised by progressive weakness that starts with the hind limbs leading to wobbly gait, wide-base stance and angled hocks. The disease... 

  for more details please click here

April  2015

     
  Dandy-Walker-Like Malformation (DWLM) in Eurasier

 

Dandy-Walker-Like Malformation (DWLM)in Purebred Eurasier Dogs with Familial Non-Progressive Ataxia DWLM is a genetic disorder found in Eurasier dogs characterised by non-progressive ataxia, symptoms have been noted in dogs at 5 – 6 weeks old. The severity of the ataxia varies between dogs, from mild truncal sway, mild lack of movement coordination, subtle dysmetric gait, imbalance and pelvic limb ataxia to severe cerebellar ataxia in puppies and episodic falling or rolling. Follow-up examinations in adult dogs showed improvement of the cerebellar ataxia and a still absent menace response. Epileptic seizures occurred in some dogs... 

  for more details please click here

April  2015

     
  Persistent Müllerian duct syndrome (PMDS) in Miniature Schnauzer

 

Muellerian ducts (paramesonephric ducts) are small structures that exist in both male and female embryos during the early fetal development, at 35-36 days of gestation, the embryo begins to differentiate into male or female. In the female, Muellerian ducts will develop to form the uterine tubes, uterus, cervix, and the upper one-third of the vagina. In the male, Muellerian ducts are lost because the testes starts producing a hormone that causes regression of the Mullerian ducts. In Miniature Schnauzer males which are affected by Persistent Müllerian duct syndrome (PMDS), the Müllerian ducts fail to regress during sexual differentiation, and therefore, all Müllerian duct derivatives, bilateral oviducts, a complete uterus with cervix and the cranial portion of the vagina, are also present... 

  for more details please click here

April  2015

     
  NEW KENNEL CLUB OFFICIAL DNA TESTING SCHEME

 

  Factor VII Deficiency in Beagle

The Kennel Club has just approved a new DNA testing scheme for Factor VII Deficiency in Beagle with Laboklin.

Factor VII deficiency is a mild bleeding disorder caused by lack of factor VII (proconvertin) which plays a role in the blood clotting system. Affected dogs bruise easily and nosebleeds maybe seen. There is often prolonged bleeding after surgery or trauma and, in the cases of major surgical procedures or trauma, bleeding maybe severe...

The mutation is also found in Airedale Terrier , Alaskan Klee Kai , Giant Schnauzer , Scottish Deerhound

  for more details please click here

 
  Cobalamin Malabsorption (Imerslund-Gräsbeck syndrome (IGS)) in Beagle

The Kennel Club has just approved a new DNA testing scheme for Cobalamin Malabsorption (Imerslund-Gräsbeck syndrome (IGS)) in Beagle with Laboklin.

Cobalamin malabsorption (merslunf-Gräsbeck Syndrome (IGS)) refers to a genetic disorder by which the vitamin B12, also known as cobalamin, fails to be absorbed from the intestine. Lack of cobalamin leads to changes in the hematopoietic system and to neurological symptoms due to irreversible damage of the brain and nervous system. Symptoms include anorexia, lethargy and failure...

The mutation is also found in Border Collie

  for more details please click here

 

April  2015

     
  Cone Degeneration (CD) by OptiGen* in Australian Shepherd, German Pointers and Alaskan Malamute

 

Although the disease is rare in general, within an affected line it is important to control the gene frequency so as to prevent producing puppies affected with the disease. The mutations causing CD in these two breeds occur in the same gene (CNGB3) but are distinct mutations and arose separately. CD disease causes day blindness due to degeneration of the retinal “cones” – cone-shaped cells in the retina that respond primarily to bright daylight. CD can be diagnosed in the early weeks of the affected dog’s life. Between 8 and 12 weeks of age, when retinal development is normally completed in dogs, signs.. 

  for more details please click here

April  2015

     
  Harlequin in Great Dane

 

The Harlequin coat colour pattern is a white coat colour with irregular patches of black or other dark colour. The Harlequin gene does not cause the Harlequin pattern without the merle gene. A Harlequin Great Dane must have both the Harlequin gene and the Merle gene. Harlequin is a merle modifier, it turns the areas between the dark patches into white, this is why Harlequin is only visible on dogs with the merle gene. Harlequin will not affect the coat colour of dogs that don't have the merle gene. Dogs without the merle gene can have the Harlequin gene but without expressing it... 

  for more details please click here

April  2015

     
  Lagotto Storage Disease (LSD)

 

The Lagotto Romagnolo storage disorder is a genetic disroder characterized by movement in-coordination, which is seen as a staggering, uncoordinated gait. Other symptoms such as involuntary eye movements (nystagmus) and behavioral changes, such as aggression, have also been seen in affected dogs. The onset of the disease varies from 4 months to 4 years. The condition is progressive and symptoms in affected worsens to a degree where they need to be euthanized... 

  for more details please click here

April  2015

     
  Juvenile Laryngeal Paralysis & Polyneuropathy (JLPP)* in Black Russian Terrier and Rottweiler

 

Juvenile Laryngeal Paralysis & Polyneuropathy (JLPP) * is a genetic disease that affects the nerves. In affected dogs, JLPP starts with the longest nerves in the body, one of the longest nerves is the one that supplies the muscles of the voice box (larynx) leading to muscle weakness and laryngeal paralysis as the first symptom. The vocal folds vibrate noisily and can obstruct the flow of air into the lungs when the dog is exercised or when it is hot. The dog may also choke on their food or water or regurgitate, and this can cause pneumonia... 

  for more details please click here

April  2015

     
  Fanconi Syndrome (FS)* in Basenji

 

Fanconi Syndrome is a genetic disease of the kidney.

In affected dogs, the Kidney's proximal tubules fail to reabsorb vitamins, minerals, sugars and other nutrients back into the body, instead they are dumped into the urine. The loss of these nutrients results in dehydration and electrolyte imbalances along with other problem.

Fanconi Syndrome is considered as one of the most common inherited disease in Basenji . Symptoms include polydipsia (excessive drinking), polyuria (excessive urination), and glucose in the urine (glucosuria). Untreated Fanconi Syndrome will lead to muscle wasting, acidosis and poor condition, and eventually death...

  for more details please click here

April  2015

     
  Hereditary Ataxia (HA) in Old English Sheepdog (Bobtail) and Gordon Setter .

 

Hereditary Ataxia (HA) is a neurodegenerative disease that affect the cerebellum causing progressive gait disturbance in both humans and dogs.

Old English Sheepdogs and Gordon Setters suffer from a juvenile onset, autosomal recessive form of canine hereditary ataxia primarily affecting the Purkinje neuron of the cerebellar cortex. The clinical and histological characteristics are similar to hereditary ataxias in humans....

 

  for more details please click here

April  2015

     
  Cerebellar Ataxia (FHA / CAFH) in Finnish Hound

 

This disease is caused by a mutation in the SEL1L gene. Affected dogs will show first indications of cerebellar neurodegeneration at the age of 4-12 weeks. First clinical signs are loss of balance, minor incoordination of gait and intention tremor while later symptoms can be a progressive incoordination or a complete loss of mobility.

 

  for more details please click here

April  2015

     
  Leonberger Polyneuropathy 1 ( LPN1)

 

The type 1 neuropathy (LPN1) in Leonberger starts at the age of 2-4 year and shows a severe progression. The symptoms of this polyneuropathy include wobbly gait and paralysis especially from the backhand. Affected dogs are not able to stand up in the final stage of the disease. Breathing noises, strange barking voice and difficulties in swallowing are other typical symptoms. The causative mutation causes around 20% of all polyneuropathy cases in the Leonberger breed. Other aetiologic mutations exist.

 

  for more details please click here

 

April  2015

     
  Progressive Retinal Atrophy (rcd3 PRA) in Chinese Crested

 

rcd3 PRA is usually found in Cardigan Welsh Corgi, it has now been identified in Chinese Crested.

Chinese Crested can now be tested for two forms of PRA, the prcd PRA and rcd3 PRA, in addition to Primary Lens Luxation (PLL).

 

The rcd3 PRA mutation was found in Chinese Crested only recently and therefore we have no information about its prevalence in the breed.

 

  for more details please click here

 

March  2015

     
  Ichthyosis in Golden Retriever *

Great News ..

Ichthyosis is Back

We are pleased to announce that, after we stopped offering this test for the past few weeks, it is now back on the list and CHEAPER than before, it is now £55.00.

Ichthyosis is part of the Kennel Club DNA Official testing Scheme in Golden Retriever.

Ichthyosis is a genetic disease causing dysfunction of the keratin in the skin, which leads to the production of large, differently pigmented skin scales. Due to the fish-like look of this scales the name was formed from the Greek word for fish: „Ichthýs“. Additionally, the pigmentation of the skin can be altered...

  for more details please click here

 

March  2015

     
  NEW KENNEL CLUB OFFICIAL DNA TESTING SCHEME

 

  Digital Hyperkeratosis (DH) (Hereditary Footpad Hyperkeratosis / Corny Feet)

The Kennel Club has just approved a new DNA testing scheme for Digital Hyperkeratosis (DH) (Hereditary Footpad Hyperkeratosis (HFH) / Corny Feet) in Irish Terrier with Laboklin.

This disease is also called “Corny Feet” as the main symptom is thickening and hardening of the footpads. Affected dogs suffer from painful cracks and crevices sometimes leading to secondary infections. Additionally, nail growth is accelerated so that nails become deformed and crumbly. As footpads and nails are cared for, the dog's lifespan and quality of life are normal...

  for more details please click here

 

February  2015

     
  LABOKLING @ CRUFTS 2015

 

 

We are pleased to inform you that LABOKLIN will be at Crufts from 5th to 8th March 2015 and we look forward to seeing you there.

 

Our stand is located in Hall 3 opposite the restaurant, it is stand number 3-7a.

 

10% discount on all DNA tests submitted at Crufts !

 

 

  for more details please click here

 

February  2015

     
  Degenerative Myelopathy

 

  LABOKLIN acquires exclusive Degenerative Myelopathy European License

We are pleased to announce that LABOKLIN acquired the exclusive European license to perform the Degenerative Myelopathy Exon 2 DNA test.

DM is a slowly progressive disease of the spinal cord. It is typically seen in older dogs after the age of 7. The disease begins with difficulty in getting up, difficulty in walking and loss of coordination in the hind limbs. It usually starts with weakness in one leg and the dog maybe seen dragging its hind paws, the disease progresses to the other leg, the dog wobbles when walking and can knuckle over. The disease continues to progress leading to complete paralysis.

DM is a devastating incurable genetic disease that has been seen frequently in a number of dog breeds in particular German Shepherd Dogs, Corgis, Boxers, Chesapeake Bay Retrievers, Rhodesian Ridgebacks, and Standard Poodles. It has also been diagnosed in American Eskimo, Golden Retriever , Labrador Retriever , Nova Scotia Duck Tolling Retriever , Shetland Sheepdog (Sheltie) , Bernese Mountain Dog , Kerry Blue Terrier , Wire Fox Terrier , Pug , Borzoi (Russian Wolfhound) , Hovawart , Soft Coated Wheaten Terrier , Canaan Dog , Great Pyrenees, and other breeds. A key feature of DM is that it is not a painful disease.

DM is caused by a DNA mutation in exon 2 of a gene called superoxide dismutase 1 (SOD1). It is referred to as DM EXON 2. This risk factor of having this gene was identified in 2009.

Recently another DM mutation was identified in Bernese Mountain Dogs in exon 1 of the SOD1 gene it is referred to as DM EXON 1.

Testing for DM EXON 2 is available for all dog breeds (including Bernese Mountain Dog). Testing for DM EXON 1 is only available for Bernese Mountain Dogs, we also offer DM EXON 1 + DM EXON 2 bundle in Bernese Mountain Dogs.

Laboklin is the only lab licensed to perform the DM EXON 2 test in Europe and samples should only be sent to our lab.

  for more details on DM EXON 2 in all dog breeds please click here

  for more details on DM EXON 1 in Bernese Mountain Dog please click here

for more details on DM EXON 1 + 2 Special Offer in Bernese Mountain Dog please click here

 

February  2015

     
  Why use an accredited laboratory

 

  LABOKLIN is a DIN EN ISO / IEC 17025 Accredited laboratory

When selecting a lab for your genetic testing, you need to be sure that you will be supplied with accurate and reliable results. The technical competence of a lab depends on a number of factors which are assessed against internationally recognised standards to demonstrate the laboratory’s competence, impartiality and performance capability. it is like a qualification LABOKLIN is a DIN EN ISO / IEC 17025 Accredited laboratory. Accreditation is provided by the German National Accreditation Body DAKKS, (in the UK by UKAS). This means that all our tests are performed according to reliable standards and verified procedures. Our laboratory is not only subject to strict daily internal controls but also to regular external controls ensuring our adherence to the strictest standards

LABOKLIN is not just about providing a test result, our genetic testing department is supported and backed by in-house specialised departments including Molecular Biology, Haematology, Serology, Pathology, Allergy, Histology, Endocrinology, Microbiology, Bacteriology and many more areas in the diagnostic spectrum since 1989.

  

 

February  2015

     
  NEW KENNEL CLUB OFFICIAL DNA TESTING SCHEME

 

  Imerslund-Gräsbeck syndrome (IGS)(Cobalamin Malabsorption) in Border Collie

Cobalamin malabsorption (merslunf-Gräsbeck Syndrome (IGS)) refers to a genetic disorder by which the vitamin B12, also known as cobalamin, fails to be absorbed from the intestine. Lack of cobalamin leads to changes in the hematopoietic system and to neurological symptoms due to irreversible damage of the brain and nervous system. Symptoms include anorexia, lethargy and failute to gain weight. Cobalamin malabsorption can be managed by supplementation with regular doses of cobalamin..

  for more details please click here

 

February  2015

     
  NEW KENNEL CLUB OFFICIAL DNA TESTING SCHEME

 

  MDR1 in Border Collie

MDR1 is a genetic disorder found in many dog breeds. Affected dogs, when treated with certain common drugs such as Ivermectin and loperamide (Imodium), are unable to pump out these drugs from the brain resulting in poisoning and neurologic symptoms ranging from tremors, anorexia and excess salivation to blindness, coma and even death. Some of these drugs such as Ivermectins, which vets prescribe extensively for the treatment of parasite infections, are able to cause toxicity at 1/200th of the dose required to cause toxicity in healthy dogs..

  for more details please click here

 

January 2015

     
  NEW KENNEL CLUB OFFICIAL DNA TESTING SCHEME

 

  Alaskan Malamute Polyneuropathy (AMPN / IPAM / HPAM)

Also known as Hereditary Polyneuropathy of Alaskan Malamute (HPAM), and Idiopathic Polyneuropathy of Alaskan Malamute (IPAM). Polyneuropathy causes undersupply of the peripheric nervous system followed by nerve degeneration. Due to the lack of nervous stimulation the muscles degrade gradually. The causal mutation in Alaskan Malamute differs from the known mutation in Greyhound breed. The Mutation in Alaskan Malamute has been investigated by Prof. Dr. Merete Fredholm together with an international team of researchers. The onset of clinical symptoms occurs during the first two years of a dog's life. These symptoms include progressive amyosthenia, exercise intolerance, loss of reflexes and ataxia of all limbs. So, the dog may fall down, walk on the tops of its feet or the gait may just look a little off. When palsy affects the larynx, changes in voice and problems in swallowing and regurgitating have also been described. The general condition is not influenced by the disease.

  for more details please click here

 
 
     
  NEW KENNEL CLUB OFFICIAL DNA TESTING SCHEMES

 

   

Hereditary Cataract in in the Boston Terrier, Staffordshire Bull Terrier and French Bulldog

 for more details please click here

Hyperuricosuria (HUU) in the Large Munsterlander  for more details please click here

Neuronal Ceroid Lipofuscinosis (NCL) in the Border Collie and Tibetan Terrier for more details please click here

Primary Lens Luxation (PLL) in the Chinese Crested & Parson Russell Terrier for more details please click here

GR (PRA1) in the Golden Retriever, PRA (cord1) in the English Springer Spaniel for more details please click here

PRA (rcd4) in the Gordon Setter and Irish Setter for more details please click here

vWD (type1) in the Manchester Terrier for more details please click here

vWD in Dutch Kooiker (Kooikerhodje). for more details please click here

 
     
  New Test

 

  Subvalvular Aortic Stenosis (SAS)

Subaortic stenosis is one of the most frequent hereditary heart failures in dogs. Due to abnormal tissue in the left ventricular outflow tract the blood flow is impeded. Symptoms show a huge variety: although dogs with a mild form of the disease may have a normal lifespan and life quality, severely affected animals may undergo life-threatening arrhythmias, congestive heart failure and sudden death. The investigated genetic variant shows a strong association with this disease. So a genetic test can help to decrease prevalence of mutation in this breed....

Subvalvular Aortic Stenosis (SAS)

 

 
     
  New Test

 

  Digital Hyperkeratosis (DH) (Hereditary Footpad Hyperkeratosis / Corny Feet)in Irish Terrier and Kromfohrländer

This disease is also called “Corny Feet” as the main symptom is thickening and hardening of the footpads. Affected dogs suffer from painful cracks and crevices sometimes leading to secondary infections. Additionally, nail growth is accelerated so that nails become deformed and crumbly. As footpads and nails are cared for, the dog's lifespan and quality of life are normal....

Digital Hyperkeratosis (DH) (Hereditary Footpad Hyperkeratosis / Corny Feet)

 

 
     
  New Test

 

  Thrombopathia (Thrombopathy) IN Basset Hound and Landseer

Thrombopathia (Thrombopathy) is an inherited disease found in Basset Hound and Landseer. It affects the blood ability to stop bleeding from damaged / injured blood vessels. Thrombocytes (Platelets) are small blood cells that respond to damage or injury of blood vessels by sticking to each other at the damaged site to plug holes until blood clotting and tissue repair can occur. In affected dogs, thrombocytes fail to respond to the damage in the blood vessel and therefore thrombocyte clumping does not occur. Affected dogs ...

Thrombopathia

 

     

October 2014

     
  Brittany Coat Colours

 

  Le Weekend Tan and Activities day Organised by the Brittany Club of Great Britain 

It was lovely meeting club members on Saturday in Catthorpe Manor to talk about coat colours in Brittany, in particular the sable coat colour.

Mansour

Notes can now be downloaded from the the following link

Brittany Coat Colours

 

February 2014

     
  NEW KENNEL CLUB OFFICIAL DNA TESTING SCHEME

 

  Degenerative Myelopathy (DM) in Nova Scotia Duck Tolling Retriever (NSDTR)

At the request of the Nova Scotia Duck Tolling Retriever breed club, the KENNEL CLUB has approved an new official DNA testing scheme for Degenerative Myelopathy in Nova Scotia Duck Tolling Retriever.

Canine degenerative myelopathy (also known as chronic degenerative radiculomyelopathy) is a progressive disease of the spinal cord in older dogs. The disease has an insidious onset typically between 7 and 14 years of age. It begins with a loss of coordination (ataxia) in the hind limbs ...

for more details please click here

 

     
     

January 2014

     
  NEW KENNEL CLUB OFFICIAL DNA TESTING SCHEME

 

  Ichthyosis in Golden Retriever

At the request of the Golden Retriever breed council, the KENNEL CLUB has approved an new official DNA testing scheme for Ichthyosis in Golden Retriever.

Ichthyosis is a genetic disease causing dysfunction of the keratin in the skin, which leads to the production of large, differently pigmented skin scales. Due to the fish-like look ...

for more details please click here

 

     
  Special Offers - Dogg

  Special offer 5: Collie Eye Anomaly (CEA)* + Hereditary Cataract  (HC) + MDR1

Only £240.00 including VAT (Save £57.50)

valid until 30/04/2014

Breed: Australian Shepherd

Please note that this offer cannot be used in conjunction with other offers such as Crufts, ABS scheme, etc.

click here for more details ..

 

  Special offer 6: OPTIGEN's prcd PRA* + EIC + HNPK + DNA Profile

ONLY £300 including VAT  (Save £87.50)

valid until 30/04/2014

Breed: Labrador Retriever

Please note that this offer cannot be used in conjunction with other offers such as Crufts, ABS scheme, etc.

click here for more details ..

 

  NEW TESTS

  Hereditary Cataract * in French Bulldog

We can now offer this test in French Bulldog in addition to Boston Terrier and Staffordshire Bull Terrier.

click here for more details ..

 

     

December 2013

  Price Reductions
     
  Furnishings and Improper Coat    reduced now £55.00 
 
  Breeds : Chinese Crested , Dachshund , German Wirehaired Pointer , Portuguese Waterdog , Various dog breeds , Havanese , Lagotto Romagnolo , Soft Coated Wheaten Terrier , Brussels Griffon , Havana Silk Dog . 
 

 

  Curly Coat     reduced now  £55.00
 
  Breeds : Border collie , Chesapeake Bay Retriever , Chihuahua , Dachshund , Kuvasz , Portuguese Waterdog , Various dog breeds , Kerry Blue Terrier , Boykin Spaniel , Havanese , Soft Coated Wheaten Terrier , Havana Silk Dog , Bishon Frise , Leonberger , Maltese . 

 

  Coat Colour: EH-locus (sable)    reduced to £55.00 or £28 when ordered as additional coat colour 
 
  Breeds : American Cocker Spaniel , English Cocker Spaniel . 
 
 

 

  Hereditary Nasal Parakeratosis (HNPK)   reduced to £95.00  N E W 
 
  Breed   : Labrador Retriever . 
 
 

 

  Juvenile epilepsy  reduced to £89.95   N E W 
 
  Breed   : Lagotto Romagnolo . 
 
 

 

  Dwarfism (Skeletal Dysplasia 2)  will be reduced to £55 starting from 21st December   N E W 
 
  Breed   : Labrador Retriever . 
 
 

 

December 2013

  Special Offers - Horse

Genetic Diseases in Horses

  Special Offer 1 for Quarter Horse (Equine):

PSSM (Polysaccharid Storage Myopathy) + HERDA (Hereditary Equine Regional Dermal Asthenia) + GBED (Glycogen Branching Enzyme Deficiency) + HYPP (Hypercalaemic Periodic Paralysis) ALL 4 tests for only £165.00 incl VAT (Save £55.00)

read more ...

 

  Special Offer 2 for American Paint Horse (Equine):

PSSM (Polysaccharid Storage Myopathy) + HERDA (Hereditary Equine Regional Dermal Asthenia) + GBED (Glycogen Branching Enzyme Deficiency) + HYPP (Hypercalaemic Periodic Paralysis) + OLWS (( Lethal White Foal Syndrome-Frame Overo)) ALL 5 tests for only £198.00 incl VAT (Save £77.00)

read more ...

 

  Special Offer 3 for Arabian Horse (Equine):

CA (Cerebellar Abiotrophy) + LFS (Lavender Foal Syndrome / Coat Colour Dilution Lethal (CCDL))+ SCID (Severe Combined Immunodeficiency) ALL 3 tests for only £148.00 incl VAT (Save...)

read more ...

 

December 2013

  Special Offers - Dog

  Special Offer 1 (Canine):

DM (Degenerative Myelopathy) + MDR1 Gene Defect + Malignant Hyperthermia (MH) + D Locus (Dilution Coat Colour) + Hyperuricosuria (HUU / SLC) All 5 tests for only £198.50 incl VAT (Save £114.00)

read more...

 

  Special Offer 2 (Canine):

MDR1 Gene Defect+ DM (Degenerative Myelopathy) + Malignant Hyperthermia (MH) + D Locus (Dilution Coat Colour) - Great offer £172.50 incl VAT for all the 4 tests. Save £85.00

read more ... 

 

  Special Offer 3 (Canine):

MDR1 Gene Defect + DM  (Degenerative Myelopathy) - Great Offer only £115 Incl VAT (Save £32.50)

read more ...

 

  Special offer 4 (Canine):

Juvenile Epilepsy + Furnishing in Lagotto Romagnolo - Great offer only £110 incl VAT (Save 34.95)

read more ...  

  

December 2013

  NEW TESTS

  CMSD (Canine Multiple System Degeneration)   in Chinese Crested , Kerry Blue Terrier . 
  Hairlessness  in Chinese Crested , Peruvian Hairless (Peruvian Inca Orchid) and Mexican Hairless Dog (Xoloitzcuintle )
  Cystinuria (Labrador Cystinuria)    in Labrador Retriever
  Cystinuria IN Australian Cattle Dog    
  Hereditary Cataract *    in Boston Terrier and Staffordshire Bull Terrier .
  Progressive Retinal Atrophy (PRA)   in Basenji
  Spinocerebellar ataxia (SCA) *  in Jack Russell Terrier and Parson Russell Terrier (PRT) . 
  pap-PRA1 (Progressive Retinal Atrophy) in Papillon and  Phalènes . 
  Hereditary Myopathy / Centronuclear Myopathy (HMLR, CNM)    in Great Dane.

 

October 2013

 

LABOKLIN offers 10% to members of the Kennel Club Assured Breeder Scheme (ABS)

 

Kennel Club Assured Breeder Scheme (ABS)

Laboklin have been working in cooperation with the Kennel Club for over five years. Many ofLaboklin DNA tests are part of the Kennel CLub Official DNA testing schemes.

 

In continuing our support for breeding healthy dogs, Laboklin is pleased to announce that members of the Kennel Club Assured Breeder Scheme (ABS) are now eligible for 10% discounton all genetic tests offered by Laboklin.

Please note that this offer cannot be used in conjunction with other offers example at Crufts, special combination discounts, etc.

 

read more ..

July 2013

 

LABOKLIN is now on facebook

What a great place to share the latest news with our customers, we will post information about new tests, schemes, events, discounts and will be able to answer many of your queries.

Please visit our facebook page http://www.facebook.com/Laboklin and like us

 

July 2013

 

LABOKLIN will be at the Manchester Pet Show on 7th & 8th September 2013.

10% Discount on all genetic tests submitted at the show (Except partner lab tests such as Optigen).

Our stand number is 134 opposite the Kennel Club stand.

Yes ... all tests including canine, feline, equine and avian ...

read more ..

July 2013

  LABOKLIN is now official Optigen partner.

For customers who would like send samples to Optigen in USA, you can now send your samples to our Manchester address and we will do everything else ... and where a Kennel Club DNA Testing Scheme is in place, results will also be recorded by the KC.

 

July 2013

  NEW TESTS

 

  Protein Losing Nephropathy (PLN) in Soft Coated Wheaten Terrier:

Protein Losing Nephropathy (PLN) is an inherited disease that affect Soft-Coated Wheaten Terriers and results in essential proteins being lost through the kidney. The disease can be mild and stable for years, however, it may lead to severe complications including kidney failure. Progression of the symptoms is variable and often influenced by environmental factors.

read more ..

  Primary Ciliary Dyskinesia (PCD) in Old English Sheepdog (Bobtail):

Primary Ciliary Dyskinesia (PCD) is an autosomal-recessive genetic disease characterized by recurrent infections of the respiratory tract as well as reduced male fertility. Around 50% of the affected dogs develop situs inversus (Kartagener syndrome).

read more ..

  Bull Terrier Polycystic Kidney Disease (BTPKD):

Polycystic Kidney Disease is a genetic slow progressing and irreversible disease characterised by the presence of cysts in the functional areas of the kidneys, The size of the cysts varies from 0.5 mm to 2.5 mm. Cysts grow and expand replacing the normal kidney tissue, as a result, the functionality of the kidneys declines, the disease is likely to end with chronic renal failure in middle to old aged dogs. The disease affects both kidneys.

read more ..

  Late Onset Ataxia (LOA) in Parson Russel Terrier (PRT):

Late onset ataxia (LOA) in the Parson Russell Terrier is a genetic disease characterised by progressive gait incoordination and loss of balance. Early symptoms are usually seen at the age of 6-12 month, the disease progresses, gait becomes increasingly incoordinated with difficulty in moving around or complete loss of mobility.

read more ..

  Pompe's Disease (Glycogen Storage Disease type II / GSDII) in Finnish Lapphund, Lapponian Herder and Swedish Lapphund:

Pompe's disease or GSDII (Glycogen Storage Disease Type II) is caused by deficiency of the acid alpha-glucosidase enzyme which leads to accumulation of glycogen in the cells, and this results in abnormal glucose levels in tissues such as cardiac, skeletal, and smooth muscle.
 

read more ..

  Cobalamin Malabsorption (Imerslund-Gräsbeck syndrome (IGS)) in Beagle and Border Collie:

Cobalamin malabsorption (merslunf-Gräsbeck Syndrome (IGS)) refers to a genetic disorder by which the vitamin B12, also known as cobalamin, fails to be absorbed from the intestine.

read more ..

  GM1-Gangliosidosis in Huskies, Portuguese Waterdog and Shiba Inu:

GM1-Gangliosidosis is a lysosomal storage disease that leads to neurological disorders. Affected dogs suffer from paralysis of the extremities and spasticity of the muscles.

read more ..

   

 

July 2013

  NEW BREEDS ADDED TO EXISTING TESTS

 

  Cavalier King Charles Spaniel can now be tested for Muscular Dystrophy (MD):

Muscular Dystrophy (MD) was only valid for Golden Retriever but now Cavalier King Charles Spaniel has been added to the affected breed list.

Muscular Dystrophy (MD) is a spontaneous, X-linked, progressively fatal disease of dogs and is also a homologue of Duchenne muscular dystrophy (DMD). Affected dogs show raised creatine kinase levels, muscle atrophy with contractures, hyaline myofiber degeneration with mineralization, endomysial and perimysial fibrosis with fatty infiltration, and cardiomyopathy.

read more ..

  American Staffordshire Terrier can now be tested for Neuronal Ceroid Lipofuscinosis (NCL):

Neuronal Ceroid Lipofuscinosis (NCL) was offered for Australian Shepherd , Border collie , Dachshund , Miniature Long Haired Dachshund , Miniature Smooth Haired Dachshund , American Bulldog , English Setter and Tibet Terrier breeds, now American Staffordshire Terrier has been added to the list.

read more ..

  LABOKLIN acquires Exclusive Worldwide License to offer Hereditary Nasal Parakeratosis (HNPK) in Labrador Retriever

Hereditary Nasal Parakeratosis a genetic disorder that causes the dog's nose to dry, especially, the upper surface of the planum forms keratinous scales, which adhere to the nose. Bloody fissures might occur in this structures, leading to chronic irritation and inflammation of the noses skin.

read more ..

  The price of Alaskan Malamute Polyneuropathy (AMPN / IPAM / HPAM) reduced to £55.00

read more ...

  NEW OFFICIAL KENNEL CLUB DNA TESTING SCHEMES WITH LABOKLIN:

 

  Primary Ciliary Dyskinesia (PCD) in Old English Sheepdog (Bobtail) )
  Pompe's Disease (Glycogen Storage Disease type II / GSDII) in Finnish Lapphund
  Musladin-Lueke syndrome (MLS) in Beagle
  Neonatal Cortical Cerebellar Abiotrophy (NCCD) in Beagle
  Hereditary Cataract in Australian Shepherd
  Collie Eye Anomaly (CEA) / Choroidal Hypoplasia (CH) BY OPTIGEN* in Australian Shepherd , Border collie , Nova Scotia Duck tolling Retriever , Shetland Sheepdog (Sheltie), Rough Collie , and Smooth Collie.
  Progressive Retinal Atrophy (rcd2-PRA) BY OPTIGEN* in Rough Collie.
  Progressive Retinal Atrophy (prcd - PRA) BY OPTIGEN* in Australian Cattle Dog, Australian Shepherd, Chinese Crested, Finnish Lapphund, Norwegian Elkhound, Poodle (Miniature), Poodle (Toy), Portuguese Water Dog, Retriever (Chesapeake Bay), Retriever (Labrador), Retriever (Nova Scotia Duck Tolling), Spaniel (Cocker) and Spanish Water Dog.
  Episodic Falling (EF) in Cavalier King Charles Spaniel
  Dry Eye and Curly Coat syndrome (CCS) in Cavalier King Charles Spaniel
  Degenerative Myelopathy (DM) / Degenerative Radiculomyelopathy in Chesapeake Bay Retriever
  Exercise Induced Collapse ( EIC ) in Labrador Retriever

 

 

 

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newsletter 01/2012

 

* test performed by partner lab

 

 

 

 

 

 
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